IGERT Nanomedicine E-Lecture

IGERT Nanomedicine E-Lecture

Date: 10/04/2011
Time: 4:30 pm – 5:30 pm
Location: 408 Ell Hall
Speaker: Dr. Anu Puri, CCR Nanobiology Program, NCI-Frederick, NIH, Frederick, MD

“Remote Activation Strategies for Localized Drug Release from Lipid-based Nanoparticles”

Successful drug delivery by the nanoparticles in the clinic relies on their biocompatibility, in vivo stability, biodegradability, and/or on demand-triggered release properties. We are developing a series of multifunctional lipid-based nanoparticles (liposomes) to improve localized drug delivery to treat cancers. I will begin with a brief introduction to the challenges and barriers that pose limitations to the success in drug delivery field. I will allude to the principles of approaches for triggered release of drug from the liposomes. The main discussion will be centered on external triggering modalities including the hyperthermia and light-activation strategies. I will share some data on the following topics.