Nano-Phenomena in Living Systems
**This symposium is cross-listed with Track VII: Mechanics of Soft and Biological Materials and Flexible Structures
B. Ji, Beijing Institute of Technology, China
X. Yi, Peking University, China
S. Zhang, The Pennsylvania State University, US
T. Saif, The University of Illinois at Urbana-Champaign
There are many nano-phenomena in living systems, including cellular uptake of nanoscale objects, the response of living cells to their three-dimensional nanomaterial environment, the roles of mechanical forces in wound healing, pathogenesis, and wound healing, etc. However, the details of how cells and tissue interact with their nanoscale environment, and the associated intra-, inter-, and extra-cellular nanoscale phenomena that influence cell behavior, are just now being elucidated. This track will focus on state of the art in understanding of nano-phenomena in living systems, especially that at the intracellular, cellular, and multicellular levels. The material factors, multi-scale modeling, and small-scale experiments that capture these behaviors in physiology, disease, and treatment will be elucidated. To the above extent, topics of interest include but are not limited to:
- Molecular Biomechanics: Protein interaction, mechanics of biomacromolecules, mechanisms of mechanosensing and mechanotransduction, interaction between membrane proteins/ion channels, mechanics of lipid molecules and lipid layers.
- Cellular and Subcellular Mechanics: Cell adhesion, cell motility, analytical and computational modeling of single cells, mechanics of cell membranes, cell migration, cell cytoskeleton and cell-extracellular matrix interactions, mechanotransduction in cells, morphogenesis, intracellular mechanics, collective bahaviors of multi-cellular system, viral budding and packaging, mechanics of subcellular structures, mechanics of cell uptake.