• Proposal: 01/17/2020


  • Amount: Up to $750,000 per year
  • Duration: Up to 5 years


The Maximizing Investigators’ Research Award (MIRA) provides support for the program of research in an investigator’s laboratory that is within the mission of NIGMS. The goal of MIRA is to increase the efficiency and efficacy of NIGMS funding. It is anticipated that this program will:

  • Increase the stability of funding for NIGMS-supported investigators, which could enhance their ability to take on ambitious scientific projects and approach problems more creatively;
  • Increase flexibility for investigators to follow important new research directions within the NIGMS mission as opportunities arise, rather than being bound to specific aims proposed in advance of the studies;
  • More widely distribute funding among the nation’s highly talented and promising investigators to increase overall scientific productivity and the chances for important breakthroughs;
  • Reduce the time spent by researchers writing and reviewing grant applications, allowing them to spend more time conducting research;
  • Enable investigators to devote more time and energy to mentoring trainees in a more stable research environment.

This FOA allows both new applications from eligible NIGMS-funded investigators and renewal applications from current established and early-stage MIRA grantees.

Eligibility & Submission Requirements

For this FOA, PDs/PIs with a previously funded ESI or EI NIGMS R35 or at least one NIGMS single-PD/PI R01-equivalent award (defined here as R01, R37, DP1, DP2, and SC1 awards) are eligible to apply. 

PDs/PIs whose only NIGMS research grant(s) is a multi-PD/PI grant(s) are not eligible to apply for a MIRA.

Please see the FOA for full eligibility details.

Contact Information

Scientific/Research Contact(s):

Zhongzhen Nie, Ph.D.
National Institute of General Medical Sciences (NIGMS)