Our research and NIH grant on isoaspartic acid's role in aging and diseases are highlighted in Northeastern news.
From NEU news: "... According to Zhou, the rate at which isoAsp forms depends on the sequence of amino acids in the protein. If asparagine sits next to the amino acid proline, it will take a long time to degrade. If it’s next to glycine, on the other hand, it may take just half a day. Luckily, there’s an antidote. The enzyme “protein isoaspartate methyltransferase,” or PIMT, can rectify the damage ..." - See more click here
Congratulations Micheal Pablo!
Micheal Pablo, an undergraduate researcher in SunnyLand, has landed a coveted co-op position at Amgen in Cambridge, Massachusetts from July to December.
An Article Highlighted in JACS Select Collection Focused on Chemical Mechanisms in Biochemical Reactions
The article, Enzyme-Catalyzed Transfer of a Ketone Group from an S-Adenosylmethionine Analogue: A Tool for the Functional Analysis of Methyltransferases, is Highlighted in JACS Select (issue 12; J Am Chem Soc, 2011, 133, 13207–13212) Collection focused on Chemical Mechanisms in Biochemical Reactions. Professor Peter J. Stang, Editor-in-Chief, commented, “Your Communication was selected because of its high scientific quality and broad appeal.”
Our Work Is Highlighted in Nachrichten aus der Chemie
Our work on keto-AdoMet as a Substrate Surrogate of Methyltransferases for Substrate Profiling and Structural Diversification (J Am Chem Soc, 2010, 132, 3642) has been highlighted in Nachrichten aus der Chemie, 2010, 58 (5), 518 Official journal of the German Chemical Society (Gesellschaft Deutscher Chemiker) Equivalent of Chemical and Engineering News of the American Chemical Society.
Congratulations Dr. Zang!
Tianzhu "Indi" Zang completed his Ph. D. in Chemistry!
Min Liu highlighted in SMP&PD Newsletter
Min Liu, Sunnyland's co-op Ph.D. student at Amgen, has been highlighted in Small Molecule Process and Product Development Newsletter for her recent paper and award from the Barnett Institute. She was featured in the SMP&PD Newsletter Volume 3 Issue 4 December 2011 for her work with VP Jerry Murry.
Sunny's paper "Zoospore interspecific signaling promotes plant infection by Phytophthora" has been accessed over 1700 times on BioMed Central, an open access publisher.