Boston harbors have been historically contaminated and uninhabitable by people and critters. Also, as a historical city, Boston's historical footprint is too small for growth. Through integrating a natural filter–the oyster–into an architectural design of a building sited on water, the project creates space within the dense urban fabric, decontaminates and filters the water of the harbor to a … See More

NanoCRISPR: An Alternative to Chemotherapy

With the increasing costs and timeliness of developing new, novel chemotherapy platforms through R & D pipelines, precedence for paradigm shifting technologies has grown. Since the advent of chemotherapeutic agents, there haven’t been viable solutions to the recurring issues of toxicity and selectivity. Any new output in developing chemotherapy platforms are born at the interface … See More

East Boston Urban Forest Initiative

Through ecological research and investigative mapping of the East Boston area, I wanted to establish a connection between the urban forest and public space networks. The East Boston Urban Forest Initiative aims to increase canopy cover in East Boston as a pilot region in part of an overall goal to increase Boston's tree canopy cover to 35% by … See More

Electrodermal Correlates of Reward Sensitivity in Emotion Perception Under Stress

Judging the emotional state of another person, such as whether he or she is angry or not, is something people do moment-to-moment in every social interaction. We examined the relationship between people's psychophysiological response to a social stress induction (a public speaking task)  and their ability to subsequently make effective judgments about facial expressions in … See More

Exploring Psychological Desire and Craving Through First-Person Experience Sampling

Buddhist philosophy provides novel theoretical insights into the relationship between desire and well-being. It suggests that destructive desires and cravings result from attaching to a particular self-concept. An enduring and inflexible view of “self” supports recurring “self-focused” desires that only bring temporary pleasure and detract from psychological well-being. Recognizing that the “self” is a fluid … See More

Get Up, Chuck!

Get Up, Chuck! is a 2D puzzle/platformer game in development for Android devices. The game stars an amorphous blob, Chuck, who solves puzzles by eating, combining and upchucking objects in the environment. The player must consider Chuck's size and weight as they move through each level. It features a cheery aesthetic, with bright, hand-drawn visuals and … See More

A Bridge to the Future: Reimagining the 21st Century City

The changing nature of society creates unplanned and often chaotic growth of urban centers. In the mid Twentieth Century, the prevalence of the automobile spawned urban flight and the creation of suburbs throughout the United States. Specifically in Boston, these developments infected the cityscape with a crippling highway system that led to a fractured city. … See More

PARP Inhibitors for Ovarian Cancer Treatment

Poly(ADP-ribose) polymerase (PARP) is a protein which plays a role in a number of DNA repair pathways. PARP inhibitors, such as Olaparib and BMN-673, act by inhibiting DNA damage repair and thus accumulating deleterious mutations leading to genetic instability. Olaparib has recently been approved for advanced ovarian cancer patients who exhibit defective BRCA1/2 genes, which … See More

Wherever I May Roam: Mapping European Telecom Company Networks and Regulatory Outcomes

In 2013 T-Mobile banished international roaming charges when visiting over 120 countries. How is this possible? T-MobileUSA is a subsidiary of Deutsche Telekom which has operations in 50 of those 120 countries. Given that global presence, T-Mobile's ability to partner with carriers in half the world seems less astounding – in fact today's telecommunications sector is dominated by … See More

Characterizing and Reducing Avoidable Out-of-Network Utilization in Healthcare

Healthcare delivery systems, long interested in minimizing outside utilization for the purpose of retaining their market share, face new and increasing incentives to keep patients inside their system in order to improve care coordination and control costs. Outside utilization, or “leakage”, occurs when patients within a health system’s designated population receive care outside of that … See More