A Comparison of the STOPP/START Criteria and the Beers Criteria as Applicable to the U.S. Nursing Home Population

Motivation: In U.S. nursing homes (NH), 40% of residents receive ≥9 different medications, which may be clinically inappropriate. The Screening Tool of Older Person’s Prescriptions (STOPP)/Screening Tool to Alert doctors to Right Treatment (START) criteria, developed in Ireland, detects potentially inappropriate medications (PIMs) and treatment omissions. The Beers criteria identify PIMs in older U.S. patients. … See More

Evaluation of Antibiotic Management in the Reduction of COPD Exacerbations

Introduction: Chronic Obstructive Pulmonary Disease (COPD) exacerbations increase morbidity and mortality. Controversy remains over the use of antibiotics during exacerbations. This study explores the clinical significance of antibiotics in COPD, and their impact on patient care. Methods: This IRB approved study retrospectively collected data from hospitalized patients admitted with a primary or secondary diagnosis of … See More

Trunk Kinematics and Neuromuscular Control in Athletes With and Without Patellofemoral Pain During a Lateral Step-Down Test

Background: Patellofemoral pain syndrome (PFPS) is a clinically challenging condition commonly occurring in athletes. PFPS has been associated with hip muscle weakness and altered neuromuscular control and lower extremity kinematics. However, the relationship between PFPS and trunk control is unclear. Purpose: The purpose of our study was to examine the relationship between trunk kinematics, neuromuscular … See More

Patterned Auditory Stimulation and Suck Dynamics in Full-Term Infants

Efficient sucking and feeding are essential skills for developing infants. However, some infants have difficulties with these tasks. Feeding difficulties often stem from lack of proper oromotor skills and coordination and can lead to extended NICU stays. Even after NICU discharge, poor sucking and feeding abilities can translate into poor breastfeeding skills. Therapies and strategies to enhance sucking and … See More

Not all Pacifiers are Created Equal: An Examination of Pacifier Types and Their Influence on Suck Patterning in Infants

Many pacifier companies state that their product is the best choice to support infant development; however, little evidence exists to support these claims. Different pacifiers can either enhance or impede proper suck development, due to the infants’ sensitivity to oral sensation cues, which have the ability to change an infant’s oromotor output. The purpose of … See More

Utilizing Rosette Nanotubes for the Delivery of siRNA for Cancer Therapeutics

Rosette Nanotubes (RNTs), a self-assembled supramolecular nanomolecule composed of fused guanine-cytosine (G^C) bases, provide a novel and innovative modality for the delivery of gene therapeutics to target cells with high efficacy. This study aims at utilizing RNTs as a nanocarrier platform for the delivery of small interfering RNA (siRNA) to knockdown oncogenic genes to facilitate … See More

Interdisciplinary Care of Patients Undergoing Liver Transplantation: Contributions of Physical Therapists as Members of the Core Team, Part 1

Introduction and Rationale. Patients undergoing liver transplantation experience pre- and postoperative complications that impact health. They experience progressive decline pre-operatively and have difficulty resuming premorbid health post-operatively. Healthcare professionals (HCPs) on transplant teams rarely include physical therapists (PTs). The purposes of this three-part project are to develop a conceptual framework to support the inclusion of PTs … See More