The mission of the Center is to translate basic science discoveries into novel antimicrobial therapies to combat Biowarfare and conventional pathogen threats. Antimicrobial drug discovery is in a state of crisis ? the last class of broad-spectrum compounds, the fluoroquinolones, was discovered 40 years ago. The rise of multidrug resistant pathogens and the threat of genetically engineered bioweapons represent an urgent need for novel antimicrobial therapies. The Center, funded by grants from the NIH, NSF, and DOE, is directed by Kim Lewis and draws faculty members from Biology, Chemistry, Physics, and Pharmaceutical Sciences. Founded in 2006.