Professors Lee Makowski and Dana Brooks, and associate professor Deniz Erdogmus, all in the Department of Electrical and Computer Engineering, have been funded by the National Science Foundation to advance imaging and signal processing for X-ray solution scattering from proteins, in order to better understand their conformational variety, which will improve functional understanding and potentially drug design.
Penny Beuning, associate professor of chemistry and chemical biology, was named an American Cancer Society Research Scholar for her work on tolerance to agents that damage DNA such as ultraviolet light, chemicals, and reactive oxygen species. The objective of her work is to understand how DNA polymerases that possess the ability to copy damaged DNA are able to distinguish between different types of damage. These findings will lead to a better understanding of how toxins in the environment lead to cancer.
Sri Sridhar, CAS Distinguished Professor in the Department of Physics, and collaborators from the Dana-Farber Cancer Institute, have secured funding from the Congressionally Directed Medical Research Programs. Their research will investigate a novel tumor therapy that combines sustained in-situ delivery of radiosensitizers to the prostate, resulting in highly efficient chemoradiation therapy with minimum toxicity and discomfort, compared with current prostate cancer treatments.
Heather Clark, associate professor of pharmaceutical science, has received a Young Faculty Award from the Defense Advanced Research Projects Agency to explore nanosensors for monitoring the behavior of electrical and chemical neurotransmitters between neurons in the brain.
Barry Bluestone, Stearns Trustee Professor and Director of the Dukakis Center for Urban and Regional Policy, and Stephanie Pollack, associate director of research, received a grant from the Barr Foundation to assist the Commonwealth of Massachusetts in developing a transportation finance campaign.