Below are peer-reviewed publications that were carried out with support from PROTECT, award number P42ES017198 from the National Institute Of Environmental Health Sciences.
The publications can be also found at NIH RePORTER website.

To see our investigator’s publications on Google Scholar or PubMed click here.


  1. Cantonwine DE, Cordero JF, Rivera-Gonzalez LO, Anzalota Del-Toro LV, Ferguson KK, Mukherjee B, Calafat AM, Ye X, Crespo N, Jimenez-Velez B, Padilla IY, Alshawabkeh AN, Meeker JD.  Urinary phthalate metabolite concentrations among pregnant women in Puerto Rico: Distribution, temporal variability, and predictorsEnviron Int, 2014; 62C:1-11. PMCID: PMC3874859 [Available on 2015/1/1] [Project 1Project 4Project 5Core C]
  2. Ferguson, Kelly K., David E. Cantonwine, Luis O. Rivera-Gonzalez, Rita Loch-Caruso, Bhramar Mukherjee, Liza V. Anzalota del Toro, Braulio Jimenez, Antonia M. Calafat, Xiaoyun Ye, Akram N. Alshawabkeh, Jose F. Cordero, and John D. Meeker. Urinary phthalate metabolite associations with biomarkers of inflammation and oxidative stress across pregnancy in Puerto Rico. Environmental Science & Technology. 2014:48(12) pp 7018-7025. PMC4066910 [Available on 2015/5/20] [Project 1]
  3. Ferguson, Kelly K., Thomas F. McElrath, Yi-An Ko, Bhramar Mukherjee, and John D. Meeker. Variability in urinary phthalate metabolite levels across pregnancy and sensitive windows of exposure for the risk of preterm birth. Environment International.   2014:70 pp 118-124. PMC4104181 [Available on 2015/9/1]  [Project 1]
  4. Ferguson KK, O’Neill MS, Meeker JD. 2014. Environmental contaminant exposures and preterm birth: A comprehensive review. J Toxicol Environ Health B Crit Rev, 16(2):69-113. PMCID: PMC3889157. [Project 1]
  5. Ferguson KK, McElrath TF, Meeker JD. 2014. Environmental phthalate exposure is associated with increased odds of preterm birthJAMA Pediatr, 168(1):61-7. PMID: 24247736. PMCID In Process. [Project 1]
  6. Fortenberry GZ, Meeker JD, Sánchez BN, Barr DB, Panuwet P, Bellinger D, Schnaas L,  Solano-González M, Ettinger AS, Hernandez-Avila M, Hu H, Tellez-Rojo MM. 2014. Urinary 3, 5, 6-trichloro-2-pyridinol (TCPY) in pregnant women from Mexico City: distribution, temporal variability, and relationship with child attention and hyperactivityInt J Hyg Environ Health, 217(2-3):405-12. PMID: 204001412. PMCID: PMC3946926 [Available on 2015-3-1]. [Project 1]
  7. Gou N, Yuan S, Lan J, Gao C, Alshawabkeh AN, Gu AZ. 2014. A quantitative toxicogenomics assay reveals the evolution and nature of toxicity during the transformation of environmental pollutants. Environmental Science & Technology.   48(15):8855-8863. PMC4123925 [Available on 2015/7/10] [Project 5]
  8. Korir ML, Knupp D, LeMerise K, Boldenow E, Loch-Caruso R, Aronoff DM, Manning SD. Association and virulence gene expression varies among serotype III group B streptococci following exposure to decidual and lung epithelial cells. Infect Immun. 2014 Aug 18. pii: IAI.02181-14. [Epub ahead of print] PMID: 25135682. PMCID — PMC Journal In Process. [Project 2]
  9. Meric D, Barbuto S, Sheahan TC, Shine JP, Alshawabkeh AN. Benchscale assessment of the efficacy of a reactive core mat to isolate PAH-spiked aquatic sediments. Soil Sediment Contam. 2014;23(1). PMCID: PMC3869623. [Available on 1/1/15] doi: 10.1080/15320383.2013.772093. [Project 5]
  10. Meric, D., Alshawabkeh, A., Shine, J.P., Sheahan, T.C. .Bioavailability of hydrophobic organic compoundsin thin-layered capped sediments. Chemosphere 103(:281-9. doi: 10.1016/j.chemosphere.2013.12.017. Epub 2013 Dec 26. PMCID: PMC3960330. [Available on 5/1/15] [Project 5]
  11. Park, Sung Kyun, Yebin Tao, John D. Meeker, Sioban D. Harlow, and Bhramar Mukherjee. 2014. Environmental risk score as a new tool to examine multi-pollutants in epidemiologic research: An example from the NHANES Study using serum lipid levels. PMC4047033. PLoS ONE 9(6): e98632. doi:10.1371/journal.pone.0098632. [Project 1]
  12. Peluso, Marco, Armelle Munnia, Valentina Bollati, Petcharin Srivatanakul, Adisorn Jedpiyawongse, Suleeporn Sangrajrang, Marcello Ceppi, Roger W. Giese, Paolo Boffetta, and Andrea Baccarelli. 2014. Aberrant methylation of hypermethylated-in-cancer-1 and exocyclic DNA adducts in tobacco smokers. Toxicological Sciences.   137(1):47-54. doi:10.1093/toxsci/kft241   [Project 3]
  13. Tong M, Yuan S, Zhang P, Liao P, Alshwabkeh AN, Xie X, Wang Y. Electrochemically Induced Oxidative Precipitation of Fe (II) for As (III) Oxidation and Removal in Synthetic Groundwater. Environ Sci Tech. 2014 May 6;48(9):5145-53. PMCID: In process. [Project 5]
  14. Yao, Y., Wang, P., Giese, R. W. (2014) Evaporative Derivatization of Phenols with 2-Sulfobenzoic Anhydride for Detection by MALDI-MS. Rapid Commun. Mass Spectrom., 28(6):653-61. PMID: 24519828. PMCID In Process. [Project 3]
  15. Yuan, S., P. Liao, and A. N. Alshawabkeh (2014) Electrolytic Manipulation of Persulfate Reactivity by Iron Electrodes for TCE Degradation in GroundwaterEnviron. Sci. Technol., 48(1):656-63. PMCID: PMC3916217. [Available on 2015/1/7] [Project 5]


  1. Anaya A., Padilla I., Macchiavelli R., and Vesper D., “Estimating Preferential Flow in Karst Aquifers using statistical mixed models.” Ground Water. 2013 Jun 26. PMCID: PMC3818453 [Available on 2014/12/26] doi: 10.1111/gwat.12084. [Project 4]
  2. Baek K., Kasem N., Ciblak A., Vesper D., Padilla I., Alshawabkeh A.N. “Electrochemical removal of selenate from aqueous solutions.” Chemical Engineering Journal. Jan 2013. Vol. 215-216, 678-684.]. PMCID: PMC3559022. [Project 5Project 4]
  3. Baek, K., A Ciblak, X Mao, EJ Kim, A Alshawabkeh (2013) “Iron Anode Mediated Transformation of Selenate in Sand Columns,” Water Research, 47(17), pp. 6538–6545. PMCID: In process. [Project 5]
  4. Boldenow, E, Jones, S, Lieberman, R.W., Chames, M.C., Aronoff, D.M., Xi, C. and Loch-Caruso, R. Antimicrobial peptide response to Group B Streptococcus in human extraplacental membranes in culture. Placenta. 34(6):480-5, 2013. PMCID: PMC3664555. [Project 2]
  5. Cantonwine DE, Hauser R, Meeker JD. Bisphenol A and Human Reproductive Health.Expert Rev Obstet Gynecol; 8(4). PMCID: PMC3811157. [Project 1]
  6. Kautz, R., Wang, P., Giese, R.W. (2013) NMR at the Picomole Level of a DNA Adduct, Chem. Res. Toxicol., 26, 1424-1429. PMCID: PMC3925674. [Available on 2014/10/21] [Project 3]
  7. Koeppe ES, Ferguson KK, Colacino J, Meeker JD. Relationship between Urinary Triclosan and Paraben Concentrations and Serum Thyroid Measures in NHANES 2007-2008. Sci Total Environ, 2013; 445-446:299-305. PMCID: PMC3572338. [Project 1]
  8. Lewis RC, Meeker JD, Peterson KE, Cantoral A, Schnaas L, Tellez-Rojo MM. Predictors of urinary bisphenol A and phthalate metabolite concentrations in Mexican children. Chemosphere, 2013; 93(10)2390-2398. PMCID: PMC3818401 [Available on 2014/11/1]. [Project 1]
  9. Meeker, J.; Cantonwine, D.; Rivera-Gonzalez, L.; Ferguson, K.; Mukherjee, B.; Calafat, A.; Ye, X.; Anzalota Del Toro, L.; Crespo, N.; Jimenez-Velez, B.; Alshawabkeh, A.; Cordero, J., ”Distribution, variability and predictors of urinary concentrations of phenols and parabens among pregnant women in Puerto Rico”, Environmental Science & Technology 2013 Apr 2;47(7):3439-47. PMCID: PMC3638245. [Project 1]
  10. Meeker JD, Benedict MD. Infertility, Pregnancy Loss and Adverse Birth Outcomes in Relation to Maternal Secondhand Tobacco Smoke ExposureCurr Womens Health Rev, 2013; 9(1):41-49. PMCID PMC3718565. [Project 1]
  11. Peluso, M. E. M., Munnia, A., Bollati, V., Srivatanakul, P., Jedpiyawongse, A., Sangrajrang, S., Ceppi, M., Giese, R. W., Boffetta, P., Baccarelli, A. A. (2013) Aberrant Methylation of Hypermethylated-in-Cancer-1 and Exocyclic DNA Adducts in Tobacco Smokers. Toxicol. Sci.135, 241. PMID: 24154486 [PubMed - in process] PMCID: PMC3871933. [Available on 2015/1/1] doi: 10.1093/toxsci/kft241. [Project 3]
  12. Peluso M., Munnia A., Ceppi M., Giese R. W., Catelan D., Rusconi F., Godschalk R. W. L., Biggeri A. “Malondialdehyde-deoxyguanosine and bulky DNA adducts in school children resident in the proximity to the Sarroch Industrial Estate on Sardinia Island, Italy” Mutagenesis. 2013 May;28(3):315-21. Epub 2013 Feb 27.  PMCID: PMC3630521. [Project 3]
  13. Sun Z, Tao Y, Li S, Ferguson KK, Meeker JD, Park SK, Batterman S, Mukherjee B. Statistical strategies for constructing health risk models with multiple pollutants and their interactions: possible choices and comparisons. Environ Health, 2013; 12(1):85. PMCID: PMC3857676. [Project 1]
  14. Tellez-Rojo MM, Cantoral A, Cantonwine DE, Schnaas L, Hu H, Peterson K, Meeker JD. Effect of prenatal phthalate exposure on neurodevelopment of children between two to three years of age. Sci Total Environ, 2013; 461-462C:386-390. PMCID: PMC3735862 [Available on 2014/9/1] [Project 1]
  15. Tetz L.M., Cheng A., Korte C., Giese R., Wang P., Harris C., Meeker J.D., Loch-Caruso, R. “Mono-2-ethylhexyl phthalate induces oxidative stress responses in human placental cells in vitro.” Toxicol Appl Pharmacol. 2013 Apr 1;268(1):47-54. Epub 2013 Jan 27.  PMCID: PMC3657603. [Project 1,  Project 2Project 3]
  16. Tetz L., Kamau P.W., Cheng A.A., Meeker J.D., and Loch-Caruso R. “Troubleshooting the dichlorofluorescein assay to avoid artifacts in measurement of toxicant-stimulated cellular production of reactive oxidant species.”J Pharmacol Toxicol Methods. 2013 Mar-Apr;67(2):56-60. Epub 2013 Feb 4. PMID: 23380227. PMCID: PMC3795613. [Project 2]
  17. Xie, W., S Yuan, X Mao, W Hu, P Liao, M Tong, AN Alshawabkeh (2013) “Electrocatalytic Activity of Pd-loaded Ti/TiO2 Nanotubes Cathode for TCE Reduction in Groundwater,” Water research, 47(11), pp. 3573-3582. [Project 5]
  18. Yuan, S., M Chen, X Mao, AN Alshawabkeh (2013) “Effects of Reduced Sulfur Compounds on Pd-catalytic Hydrodechlorination of TCE in Groundwater by Cathodic H2 under Electrochemically-induced Oxidizing Conditions,” Environ. Sci. Technol., 2013, 47 (18), pp 10502–10509. [Project 3Project 5]
  19. Yuan, S., Gou, N., Alshawabkeh, A. N. and Gu, A. Z. (2013) “Efficient degradation of contaminants of emerging concerns by a new electro-Fenton process with Ti/MMO cathode,” Chemosphere, 93(11), pp. 2796–2804. PMCID In process. [Project 5]
  20. Yuan S., Chen M., Mao X., Alshawabkeh A. N., “A Three-electrode Column for Pd-Catalytic Oxidation of TCE in Groundwater with Automatic pH-regulation and Resistance to Reduced Sulfur Compound Foiling.” Water Res. Jan 2013 1;47(1):269-78. Epub 2012 Oct 13. PMCID: PMC3581803. [Project 5]


  1. Ciblak A., Mao X., Padilla I., Vesper D., Alshawabkeh I., Alshawabkeh A. N. “Electrode effects on temporal changes in pH and redox potential in electrolytes for water treatment.” Environmental Science and Health Part A. 2012. Volume 47, Issue 5, pp 718-726.  PMCID: PMC3329560.[Project 5Project 4]
  2. Cordero JF, Meeker JD, Sheahan T, Padilla I, Giese R, Silevitch MB, Loch-Caruso R, Kaeli D, Alshawabkeh A. Case Study: Puerto Rico Testsite for Exploring Contamination Threats. Geotechnical Special Publication (225  GSP):3553-3562. [Project 1Project 2, Project 3Project 4Project 5Core CCore DCore BCore E]
  3. Ferguson K., Loch-Caruso R., Meeker J.  ”Exploration of oxidative stress and inflammatory markers in relation to urinary phthalate metabolites: NHANES 1999-2006.”  Environmental Science & Technology. Jan 2012. 46(1):477-85. Epub 2011 Dec 1. PMCID: PMC3258337. [Project 1Project 2]
  4. Ferguson K.K., Hauser R., Altshul L., Meeker J.D. “Serum concentrations of p,p’-DDE, HCB, PCBs and reproductive hormones among men of reproductive age.” Reprod Toxicol. Nov 2012. 34(3):429-435. PMCID: PMC3419818. [Project 1]
  5. Fortenberry G.Z., Hu H., Turyk M., Barr D. B., Meeker J. D. “Association between urinary 3, 5, 6-trichloro-2-pyridinol, a metabolite of chlorpyrifos and chlorpyrifos-methyl, and serum T4 and TSH in NHANES 1999-2002.” Sci Total Environ. May 2012. 1;424:351-5. Epub 2012 Mar 17. PMCID: PMC3327766 [Project 1]
  6. Gent D. B., Wani A., Alshawabkeh A. N.  “Experimental Design for One Dimensional Electrolytic Reactive Barrier for Remediation of Munition Constituent in Groundwater”, Electrochimica Acta. Dec 2012. V. 86, 130-137. PMCID: PMC 3587050. [Project 5]
  7. Ghasemizadeh R., Hellweger F., Butscher C., Padilla I., Vesper D., Field M., Alshawabkeh A. N. ”Review: Groundwater flow and transport modeling of karst aquifers, with particular reference to the North Coast limestone aquifer system of Puerto Rico.” Hydrogeology Journal. Dec 2012. Volume 20, Issue 8, pp 1441-1461. PMCID: PMC 3640320. [Project 4]
  8. Latorre I., Hwang S., Montalvo R. “Isolation and Molecular Identification of Landfill Bacteria Capable of Growing on Di-(2-ethylhexyl) Phthalate and Deteriorating PVC Materials”. Journal of Environmental Science and Health. 2012. Part A 47(14), 2254-2264. PMCID: PMC3432978. [Project 4]
  9. Latorre I., Hwang S., Sevillano M. Montalvo R. “PVC Biodeterioration and DEHP Leaching by DEHP-degrading Bacteria.” International Biodeterioration & Biodegradation. Apr 2012. Volume 69, Pages 73–81. PMCID: PMC3377483. [Project 4]
  10. Mao X., Yuan S., Fallahpour N., Ciblak A., Howard J., Padilla I., Loch-Caruso R., Alshawabkeh A. N. “Electrochemically induced dual reactive barriers for transformation of TCE and mixture of contaminants in groundwater.” Environ Sci Technol, Nov 2012. 6;46(21):12003-11. Epub 2012 Oct 15. PMCID: PMC3310245. [Project 5Project 4 & Project 2]
  11. Mao X., Wang J., Ciblak A., Cox E. E., Riis C., Terkelsen M., Gent D. B., Alshawabkeh A. N.  ”Electrokinetic-enhanced bioaugmentation for remediation of chlorinated solvents contaminated clay.”  J Hazard Mater. Apr 2012. 30;213-214:311-7. Epub 2012 Feb 9.  PMCID: PMC3310245; Publ.ID: HAZMAT13988. [Project 5]
  12. Mao X., Ciblak A., Baek K., Amiri M., Loch-Caruso R., Alshawabkeh, A. N. “Optimization of electrochemical dechlorination of trichloroethylene in reducing electrolytes,” Water Research. Apr 2012. Volume 46, Issue 6 Pages 1847–1857. PMID: 22264798 PMCID: PMC3288245. [Project 5 & Project 2]
  13. Meeker J.  ”Exposure to environmental endocrine disruptors and child development,” Arch Pediatr Adolesc Med. Jun 2012 1;166(6):E1-7.  PMCID: PMC3572204. [Project 1]
  14. Meeker J.D., Ferguson K.K. Male Reproductive Tract Disorders. In: Weiss B (ed). Aging and Vulnerability to Environmental Chemicals. Royal Society of Chemistry. Cambridge, UK: 2012. [Project 1]
  15. Meeker J. D., Ferguson K. K. “Phthalates: Human exposure and related health effects.” Dioxins and Persistent Organic Pollutants: Health and Toxicity, Third Edition. Mar 2012. [Project 1]
  16. Meeker J.D., Ferguson K.K. “Relationship between Urinary Phthalate and Bisphenol A Concentrations and Serum Thyroid Measures in U.S. Adults and Adolescents from NHANES 2007-08.” Environ Health Perspect. 2012. PMCID: PMC3230451. [Project 1]
  17. Meeker J.D., Calafat A.M., Hauser R. “Urinary phthalate metabolites and their biotransformation products: predictors and temporal variability among men and women.” J Expo Sci Environ Epidemiol. Jul 2012. 22(4):376-85. doi: 10.1038/jes.2012.7. Epub 2012 Feb 22. PMCID: PMC3412392. [Project 1]
  18. Paz-Garcia J. M., Baek K., Alshawabkeh I. D., Alshawabkeh A. N. “A Generalized  Model for Enhanced Transport of Contaminants in Soil by Electric Fields.” Journal of Environmental Science and Health, Part A. 2012. Volume 47, Issue 2. PMID: 22242884 PMCID: PMC3267327. [Project 5]
  19. Peluso M., Munnia A., Piro S., Jedpiyawongse A., Sangrajrang S., Giese R.W., Ceppi M., Boffetta P., Srivatanakul P. “Fruit and vegetable and fried food consumption and 3-(2-deoxy-β-D-erythro-pentafuranosyl)pyrimido[1,2-α]purin-10(3H)-one deoxyguanosine adduct formation”, Free Radical Research. Jan 2012. 46(1):85-92. Epub 2011 Dec 1. PMCID: PMC3293701. [Project 3]
  20. Sarahney H., Mao X.,  Alshawabkeh A. N. “The Role of Iron Anode Oxidation on Transformation of Chromium by Electrolysis.” Electrochimica Acta, Dec 2012. V. 86, 96-101. PMCID: PMC3532856. [Project 5]
  21. Wang P., Gao J., Li G., Shimelis O., Giese R.W. “Nontargeted Analysis of DNA Adducts by Mass-Tag MS: Reaction of p-Benzoquinone with DNA.” Chem. Res. Toxicol. Dec 2012. 25, 2737-2743. PMID: 23113579 PMCID: PMC3527073. [Project 3]
  22. Wang P., Fisher D., Rao A., Giese R. ”Nontargeted Nucleotide Analysis Based on Benzoylhistamine Labeling-MALDI-TOF/TOF-MS: Discovery of Putative 6-Oxo-Thymine in DNA.” Anal Chem. Apr 2012. 17;84(8):3811-9. Epub 2012 Apr 2.  PMCID: PMC3341171. [Project 3]
  23. Wickerham E.L., Lozoff B., Shao J., Kaciroti N., Xia Y., Meeker J.D.  ”Reduced birth weight in relation to pesticide mixtures detected in cord blood of full-term infants.”  Environ Int. 2012 Oct 15;47:80-5. Epub 2012 Jul 13.  PMCID: PMC3410737. [Project 1]
  24. Wu X., Gent D. B., Davis J.L., Alshawabkeh A. N. ”Lactate Injection by Electric Currents for Bioremediation of Tetrachloroethylene in Clay.” Electrochimica Acta. Dec 2012. V. 86, 157-163. PMCID: PMC3524988 [Project 5]
  25. Yuan S., Mao X., Alshawabkeh A. ”Efficient Degradation of TCE in Groundwater Using Pd and Electro-generated H2 and O2: A Shift in Pathway from Hydrodechlorination to Oxidation in the Presence of Ferrous Ions.” Environmental Science & Technology. Mar 2012. Volume 46, Number, pp 3398–3405.  PMCID: PMC3319670. [Project 5]


  1. Ferguson K.K., Loch-Caruso R., Meeker J.D. “Urinary phthalate metabolites in relation to biomarkers of inflammation and oxidative stress: NHANES 1999-2006.” Environ Res. Jul 2011. 111(5):718-26. Epub 2011 Feb 23. PMID: 21349512 PMCID: PMC3110976. [Project 1Project 2]
  2. Mao X., Ciblak A., Amiri M., Alshawabkeh A.N.  ”Redox Control for Electrochemical Dechlorination of Trichloroethylene in Bicarbonate Aqueous Media.” Environ Sci Technol. Jul 2011. PMCID: PMC3150566. [Project 5]
  3. Padilla I. “Historical Contamination Of Groundwater Resources In The North Coast Karst Aquifers Of Puerto Rico.” Dimension, a publication of the Puerto Rico Professional College of Engineers and Land Surveyors. PMCID: PMC3999440. [Project 4]
  4. Pelluso M., Munnia A., Risso G.G., Piro S., Ceppi M., Giese R. W., Brancato B. “Breast fine-needle aspiration malondialdehyde deoxyguanosine adduct in breast cancer.” Free Radical Research. Apr 2011. 45(4):477-82. Epub 2011 Jan 21. PMID: 21250785 PMCID: PMC3315697. [Project 3]


  1. Bono R., Romanazzi V., Munnia A., Piro S., Allione A., Ricceri F., Guarrera S., Pignata C., Matullo G., Wang P., Giese R.W., Peluso M. “Malondialdehyde-Deoxyguanosine Adduct Formation in Workers of Pathology Wards: The Role of Air Formaldehyde Exposure.” Chemical Research in Toxicology. Aug 2010. 23(8):1342-1348. PMID: 2070740. PMCID: PMC2924748. [Project 3]
  2. Cantonwine D., Meeker J., Hu H., Sanchez B., Lamadrid-Figueroa H., Mercado-Garcia A., Fortenberry G., Calafat A., Tellez-Rojo M.M. “Bisphenol A exposure in Mexico City and risk of prematurity: a pilot nested case control study.” Environmental Health. Oct 2010. 9:62. PMID: 20955576 PMCID: PMC2965706. [Project 1]
  3. Thiex N.W., Chames M.C., Loch-Caruso R.K. “Tissue-specific induction of COX-2 and prostaglandins in lipopolysaccharide-stimulated extraplacental human gestational membranes in a 2-chamber transwell culture system.”  Reprod Sci. Dec 2012. 17(12):1120-9. Epub 2010 Sep 22. PMID: 20861394 PMCID: PMC3096444. [Project 2]


  1. Meeker J.D., Hu H., Cantonwine D.E, Lamadrid-Figueroa H., Calafat A.M., Ettinger A.S., Hernandez-Avila M., Loch-Caruso R., Tellez-Rojo M.M. “Urinary phthalate metabolites in relation to preterm birth in Mexico City.” Environ Health Perspect. Oct 2009. 117 (10). PMID: 20019910 PMCID: PMC 2790514. [Project 1]