PROTECT’s Meeker & Ferguson Relate BPA, Altered Thyroid Hormones

Project 1 leader John Meeker and his graduate student Kelly Ferguson have jointly published a paper in Environmental Health Perspectives that links BPA and altered thyroid activity.

As told by the U. of Michigan News Service:

ANN ARBOR, Mich.—A link between chemicals called phthalates and thyroid hormone levels was confirmed by the University of Michigan in the first large-scale and nationally representative study of phthalates and BPA in relation to thyroid function in humans.

The U-M School of Public Health study also reported suggestive findings consistent with a previously reported link between a chemical called bisphenol-A and thyroid hormone levels. BPA is best known for its use in certain plastic water bottles and in the linings of canned foods.

Researchers used publicly available data from the U.S. National Health and Nutrition Examination Survey to compare urine metabolites and serum thyroid measures from 1,346 adults and 329 adolescents. Generally speaking, greater concentrations of urinary phthalate metabolites and BPA were associated with greater impacts on serum thyroid measures, said John Meeker, assistant professor at U-M SPH and lead study author.

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The story was also covered by NIEHS here.

Download the paper here.

Citation:Meeker JD, Ferguson KK. 2011. Relationship between urinary phthalate and bisphenol A concentrations and serum thyroid measures in U.S. adults and adolescents from NHANES 2007-08. Environ Health Perspect; doi:10.1289/ehp.1103582; [Online 11 July 2011].