The Physical Genome

When: Thursday, February 26, 2015 at 4:00 pm
Where: DA 114
Speaker: Jane Kondev
Organization: Physics and Quantitative Biology, Brandeis University
Sponsor: Physics Colloquium

Every day there seems to be a story in the news about DNA and the genes that it encodes. While this abstraction of DNA as an information storage device is useful, in this talk I will consider the physical nature of DNA. Namely, DNA is a long, flexible, negatively charged molecule and its physical properties affect a number of critical functions that it performs in the cell. One such function is to turn on and off the production of proteins, which are the building blocks of the cell, in response to different physical and chemical ques. Another is to repair itself when it is broken. In this talk I will describe how simple physics models combined with experiments on cells and single molecules are being used to develop a quantitative understanding of the physical genome.

Host: Assistant Professor Meni Wanunu