S. John Gatley
Director of Graduate Programs
Office: Room 123, The Fenway
B.Sc. University of Durham, U.K., 1970;
M.Sc. University of Newcastle-upon-Tyne, U.K., 1971;
Ph.D. University of Newcastle-upon-Tyne, U.K.,1975
Major Research Areas
Current research in John Gatley's laboratory pertains to radiotracer technology and radionuclide imaging. He is currently funded by the U.S. Department of Energy to evaluate lipid signaling systems in biological systems including plants and animals. Recent work has included NIH-funded studies of the design, synthesis and radiolabeling of radiotracers for imaging cannabinoid receptors and other molecular targets involved in drug dependence, and NASA-funded work on brain damage caused by the space radiation environment.
Duclos RI Jr, Johnston M, Vadivel SK, Makriyannis A, Glaser ST, Gatley SJ. A methodology for radiolabeling of the endocannabinoid 2-arachidonoylglycerol (2-AG). J Org Chem. 2011 Apr 1;76(7):2049-55.
Duclos RI, Gatley SJ, Bhatt SR, Johnston M. The preparation of 2-O-[1'-C]arachidonoyl-1-O-stearoyl-sn-glycerol. J Labelled Comp Radiopharm. 2009 Jun 1;52(8):324-326.
Rice OV, Grande AV, Dehktyar N, Bruneus M, Robinson JK, Gatley SJ. Long-term effects of irradiation with iron-56 particles on the nigrostriatal dopamine system. Radiat Environ Biophys. 2009 Apr;48(2):215-25.
Gifford AN, Espaillat MP, Gatley SJ. Biodistribution of radiolabeled ethanol in rodents. Drug Metab Dispos. 2008 Sep;36(9):1853-8.
Gifford AN, Makriyannis A, Volkow ND, Gatley SJ. In vivo imaging of the brain cannabinoid receptor. Chem Phys Lipids. 2002 121:65-72.