For decades, the inner workings of a protein implicated in the cause of nearly 30 percent of all cancers baffled drug developers. But chemistry professor Carla Mattos may have unlocked the mystery.
(with Buhrman, G., O‚ÄôConnor, C., Zerbe, B., Kearney, B. M., Napoleon, R., Kovrigina, E. A., Vajda, S., Kozakov, D., and Kovrigin, E. L.) Journal of Molecular Biology, 413, 773-789 (2011).
(with Burhman, G., Kumar, S., Cirit, M., and Haugh, J. M.) Journal of Biological Chemistry, 286, 3323-3331 (2011).
(with Buhrman, G., Holzapfel, G., and Fetics, S.) PNAS, 107, 4931-4936 (2010).