Faculty Experts

Alexandros Makriyannis

George D. Behrakis Chair in Pharmaceutical Biotechnology, Director of the Center for Drug Discovery, Professor of Chemistry and Chemical Biology



Related Articles

Structure of the brain’s ‘marijuana receptor’ revealed

New research by an inter­dis­ci­pli­nary team, including Northeastern’s Alexan­dros Makriyannis, reveals how THC—the psy­choac­tive ingre­dient in marijuana—gets into brain cells. The find­ings open the door to the devel­op­ment of new med­ica­tions, free from side effects, for con­di­tions from pain and obe­sity to neu­ro­log­ical dis­eases and addiction.

10/19/16 - BOSTON, MA. -  Alexandros Makriyannis
Professor, George D. Behrakis Endowed Chair, and Director of the Center for Drug Discovery poses for a portrait on Oct. 19, 2016. Photo by Matthew Modoono/Northeastern University

Drug discovery and delivery research at Northeastern’s pharmacy school spurs innovation, collaboration

Throughout Northeastern’s School of Phar­macy, researchers are making progress in solving a range of pressing health challenges.

Drug discovery and delivery research at Northeastern’s pharmacy school spurs innovation, collaboration

An off-​​switch for drugs’ toxic side effects

New research from the Center for Drug Dis­covery at North­eastern presents a series of mol­e­cules that can be con­trol­lably deac­ti­vated, thereby reducing the side effects of poten­tially valu­able drugs.

Alexandros Makriyannis

An interdisciplinary approach to drug-​​abuse research

The Center for Drug Dis­covery at North­eastern hosted the 10th annual sym­po­sium on cur­rent trends in drug-​​abuse research ear­lier this month.

Alexandros Makriyannis

Professor honored for his contributions to medicinal chemistry

Alexan­dros Makriyannis, the founding director of Northeastern’s Center for Drug Dis­covery, has received the annual Award in Med­i­c­inal Chem­istry from the Amer­ican Chem­ical Society.


Northeastern explores biotech collaboration with Algeria

A del­e­ga­tion of Algerian gov­ern­ment offi­cials met last week with Pres­i­dent Joseph E. Aoun and fac­ulty mem­bers in the Bouvé Col­lege of Health Sci­ences with the hope of forging part­ner­ships in the biotech­nology sector.

Photo by Christopher Huang.

New weight-​​loss compound shows promise

Northeastern’s Center for Drug Dis­covery col­lab­o­rates with National Insti­tutes of Health on a ther­a­peutic drug that could aid weight loss without side effects

Pharmaceutical Biotech Scientist Discovers New Molecule to Treat Chronic Pain

North­eastern Uni­ver­sity Phar­ma­ceu­tical Sci­ences pro­fessor and Center for Drug Dis­covery director Alexan­dros Makriyannis and a team of researchers have cre­ated a syn­thetic mol­e­cule that could be used to treat chronic […]

Selected Publications

For a complete list of faculty citations, please visit iRis, Northeastern’s digital archive.


Dietary docosahexaenoic acid supplementation alters select physiological endocannabinoid-system metabolites in brain and plasma

(with Wood J.T., J.S. Williams, L. Pandarinathan, D.R. Janero, and C.J. Lammi-Keefe) J. Lipid Res., 51(6), 1416-1423.


Mass spectrometry-based GPCR proteomics: Comprehensive characterization of the human cannabinoid 1 receptor

(with Zvonok N., W. Xu, J. Williams, D.R. Janero, and S.C. Krishnan) J. Proteome Res., 9(4), 1746-1753.


The neutral cannabinoid CB(1) receptor antagonist AM4113 regulates body weight through changes in energy intake in the rat

(with Cluny N.L., A.P. Chambers, V.K. Vemuri, J.T. Wood, L.K. Eller, C. Freni, R.A. Reimer, and K.A. Sharkey) Pharmacol. Biochem. Behav., 97(3), 537-543.

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