Northeastern University


Examples of Publications by ECRP Staff

Kao, C-Y., Giese, R.W. (2005) Measurement of N7-(2'-Hydroxyethyl)guanine in Human DNA by Gas Chromatography Electron Capture Mass Spectrometry, Chem. Res. Toxicol. 18, 70-75.

Yong. L. C., Schulte, P. A., Kao, C-K., Giese, R. W., Boeniger, M. F., Strauss, G. H.S., Petersen, M. R., Wiencke, J. K. (2007) DNA Adducts in Granulocytes of Hospital Workers Exposed to Ethylene Oxide, Am. J. Ind. Med., 50, 293-302.09.

Jarosz, D. F., Beuning, P. J., Cohen, S. E., Walker, G. C. (2007) Y-Family DNA Polymerase in Escherichia coli, Trends in Microbiol. 15, 70-77.

Yong. L. C., Schulte, P. A., Kao, C-K., Boeniger, M. F., Strauss, G. H.S., Petersen, M. R., Wiencke, J. K., Giese, R. W. (2007) DNA Adducts in Granulocytes of Hospital Workers Exposed to Ethylene Oxide, Am. J. Ind. Med., 50, 293-302.

Ding, Y., Paonessa, J.D., Randall, K.L., Argoti, D., Chen, L., Vouros, P., Zhang, Y., Sulforaphane inhibits 4-Aminobiphenyl-induced DNA Damage in Bladder Cells and Tissues” Carcinogenesis, 31, 199-2003 (2010).

Jing Fang, Kasper D. Rand, Michelle C. Silva, Thomas E. Wales, John R. Engen, and Penny J. Beuning (2010) “Conformational Dynamics of the Escherichia coli polymerase manager proteins UmuD and UmuD′ ” Journal of Molecular Biology 398 40-53.

Jaylene N. Ollivierre*, Jing Fang*, and Penny J. Beuning (2010) “The roles of UmuD in regulating mutagenesis” Journal of Nucleic Acids Article ID 947680, 12 pages, 2010. doi:10.4061/2010/947680.

Bono, R., Romanazzi, V., Munnia, A., Piro, S., Allione, A., Ricceri, F., Guarrera, S., Pignata, C., Matullo, G., Wang, P. Giese, R. W., Peluso, M. (2010) Malondialdehyde-Deoxyguanosine Adduct Formation in Workers of Pathology Wards: The Role of Air Formaldehyde Exposure, Chem. Res. Toxicol. 23, 1342-1348. PMCID:20707408.

Peluso, M., Munnia, A., Risso, G. G., Catarzi, S., Piro, S., Ceppi, M., Giese, R. W., Brancato, B. (2011) Breast fine-needle aspiration malondialdehyde deoxyguanosine adduct in breast cancer, Free Radical Res. 45, 477-482. PMCID:21250785.

Peluso, M., Munnia, A., Piro, S., Jedpiyawongse, A., Sangrajrang, S., Giese, R. W., Ceppi, M., Boffetta, P. Srivatanakul, P. (2011) Fruit and vegetable and fried food consumption and 3-(2-deoxy-β-D-erythro-pentafuranosyl)pyrimido[1,2-α] purin-10(3H)-one deoxyguanosine adduct formation, Free Radical Res. 46, 85-92. PMCID:22081860.

Discrimination against the cytosine analog tC by Escherichia coli DNA polymerase IV DinB. Walsh JM, Bouamaied I, Brown T, Wilhelmsson LM, Beuning PJ. Journal of molecular biology. 2011; 409(2):89-100. PMID: 21477595

Escherichia coli processivity clamp β from DNA polymerase III is dynamic in solution. Fang J, Engen JR, Beuning PJ. Biochemistry. 2011; 50(26):5958-68. NIHMSID: NIHMS302906 PMID: 21657794 PMCID: PMC3130017

Characterization of Escherichia coli UmuC active-site loops identifies variants that confer UV hypersensitivity. Hawver LA, Gillooly CA, Beuning PJ. Journal of bacteriology. 2011; 193(19):5400-11. PMID: 21784925 PMCID: PMC3187380

Electron spin labeling reveals the highly dynamic N-terminal arms of the SOS mutagenesis protein UmuD. Ollivierre JN, Budil DE, Beuning PJ. Molecular bioSystems. 2011; 7(12):3183-6. PMID: 21975937

Wang, P., Fisher, D., Rao, A., Giese, R.W. (2012) Nontargeted Nucleotide Analysis Based on Benzoylhistamine Labeling-MALDI-TOF/TOF-MS: Discovery of Putative 6-Oxo-Thymine in DNA, Anal. Chem. 84, 3811-3819. PMCID:22409256.

Wang, P., Gao, J., Li, G., Shimelis, O., Giese, R. W. (2012) Nontargeted Analysis of DNA Adducts by Mass-Tag MS: Reaction of p-Benzoquinone with DNA, Chem. Res. Toxicol. 25, 2737-2743. PMCID:23113579.

Synthetic nucleotides as probes of DNA polymerase specificity. Walsh JM, Beuning PJ. Journal of nucleic acids. 2012; 2012:530963. PMID: 22720133 PMCID: PMC3377560

Selective disruption of the DNA polymerase III α-β complex by the umuD gene products. Silva MC, Nevin P, Ronayne EA, Beuning PJ. Nucleic acids research. 2012; 40(12):5511-22. PubMed PMID: 22406830 PMCID: PMC3384344

Multiple strategies for translesion synthesis in bacteria. Ippoliti PJ, Delateur NA, Jones KM, Beuning PJ. Cells. 2012; 1(4):799-831. PMID: 24710531 PMCID: PMC3901139

Effects of non-catalytic, distal amino acid residues on activity of E. coli DinB (DNA polymerase IV). (2012) Walsh JM, Parasuram R, Rajput PR, Rozners E, Ondrechen MJ, et al. Environmental and molecular mutagenesis. 2012; 53(9):766-76. PMID: 2303473

Jason M. Walsh, Ramya Parasuram, Pradyumna R. Rajput, Eriks Rozners, Mary Jo Ondrechen and Penny J. Beuning (2012) "Effects of non-catalytic, distal amino acid residues on activity of E. coli DinB (DNA Polymerase IV)" Environmental and Molecular Mutagenesis 53 766-776. PMID: 23034734

Tetz, L, M., Cheng, A. A., Korte, C. S., Giese, R. W., Wang, P., Harris, C., Meeker, J. D., Loch-Caruso, R. (2013) Mono-2-ethylhexyl phthalate induces oxidative stress responses in human placental cells in vitro, Toxicol. Appl. Pharmacol. 268, 47-54. PMCID:2336088.

Ollivierre, J. N., Sikora, J. L., Beuning, P. J. (2013) Dimer exchange and cleavage specificity of the DNA damage response protein UmuD, Biochimica et Biophysica Acta-Proteins and Proteomics 1834 611-620.

Kautz, R., Wang, P., Giese, R.W. (2013) NMR at the Picomole Level of a DNA Adduct, Chem. Res. Toxicol., 26, 1424-1429. PMCID 24027148.

Hawver LA, Beuning PJ. Second ed. Lennarz WJ, Lane MD, editors. San Diego: Elsevier Science; 2013. Chapter 486, UmuC D Lesion Bypass DNA Polymerase V; p.477-481.

Dimer exchange and cleavage specificity of the DNA damage response protein UmuD. Ollivierre JN, Sikora JL, Beuning PJ. Biochimica et Biophysica Acta. 2013; 1834(2):611-20. PubMed 23220418

Discrimination against major groove adducts by Y-family polymerases of the DinB subfamily. Walsh JM, Ippoliti PJ, Ronayne EA, Rozners E, Beuning PJ. DNA repair. 2013; 12(9):713-22. PMID: 23791649

Peluso, M., Munnia, A., Tarocchi, M., Arciello, M., Balsano, C., Giese, R. W., Galli, A. (2014) Exocyclic DNA Adducts in a Murine Model of Non-alcoholic Steatohepatitis. J. Carcinogen Mutagen, S3:003. doi: 10.4172/2157-2518. S3-003.

Chemical Biology of Nucleic Acids: Fundamentals and Clinical Applications Nevin P, Beuning PJ. Erdmann VA, Markiewicz WT, Barciszewski J, editors. Berlin: Springer; 2014. Use of FRET to study dynamics of DNA replication; p.95-111.

Cryptocaryol Structure-Activity Relationship Study of Cancer Cell Cytotoxicity and Ability to Stabilize PDCD4. Cuccarese MF, Wang Y, Beuning PJ, O'Doherty GA. ACS Medicinal Chemistry Letters. 2014; 5(5):522-6.

Peluso, M.E., Munnia, A., Giese, R. W., Catelan, D., Rocca, S., Farigu, S., Leoni, A., Bruzzone, M., Ceppi, M., and Biggeri, A.(2015) Exocyclic DNA adducts in sheep with skeletal fluorosis resident in the proximity to the Portoscuso-Portovesme industrial estate on Sardinia Island, Italy, Toxicol. Res., 4, 986-993, DOI: 10.1039/C5TX00045A.

Wang, P., Zhang, Q., Yao, Y., Giese, R.W. (2015) Cationic Xylene Tag for Increasing Sensitivity in Mass Spectrometry, J. Am. Soc. Mass Spectrom. 26, 1713-1721, DOI: 10.1007/s13361-015-1200-4.

Steric gate residues of Y-family DNA polymerases DinB and pol kappa are crucial for dNTP-induced conformational change" Philip Nevin, John R. Engen, and Penny J. Beuning DNA Repair 29 65-73 (2015).

Non-cognate DNA damage prevents formation of active conformation of Y-family DNA polymerases DinB and pol kappa" Philip Nevin, Xueguang Lu, Ke Zhang, John R. Engen, and Penny J. Beuning The FEBS Journal 282 2646–2660 (2015).

Point mutations in Escherichia coli DNA pol V that confer resistance to non-cognate DNA damage also alter protein-protein interactions" Lisa A. Hawver, Mohammad Tehrani, Nicole M. Antczak, Danielle Kania, Stephanie Muser, Jana Sefcikova and Penny J. Beuning Mutation Research 780 1-14 (2015).

Yao, Y., Wang, P., Shao, G., Anzalota Del Toro, L. V., Codero, J., Giese, R. W. (2016) Nontargeted analysis of the urine nonpolar sulfateome: a pathway to the nonpolar xenobiotic exposome, Rapid Commun. Mass Spectrom. 30, 2341-2350.

Wang, P., Giese, R.W. (2017) Recommendations for quantitative analysis of small molecules by matrix-assisted laser desorption ionization mass spectrometry, J. Chromatogr. A, 1486, 35-41.

Cellai, F., Munnia, A., Viti, J., Doumett, S., Ravagli, C., Ceni, E., Mello, T., Giese, R. W., Baldi, G., Galli, A., Peluso, M. (2017) Magnetic hyperthermia and oxidative damage to DNA on human hepatocarcinoma cells, int. J. Mol. Sci., in press.

Munnia, A., Giese, R.W., Polvani, S., galli, A., Cellai, F., Peluso, M. E. M. (2017) Bulky DNA Adducts, Tobacco Smoking, Genetic Susceptibility, and Lung Cancer Risk, Adv. Clin. Chem. In press.