Publications

Boston Puerto Rican Health Study

Tucker KL. Stress and nutrition in relation to excess development of chronic disease in Puerto Rican adults living in the Northeastern USA. J Med Invest. 2005 Nov;52 Suppl:252-8. (J Med Invest)
Artinian N, Warnecke RB, Kelly KM, Weiner J, Lurie N, Flack JM, Mattei J, Eschbach K, Long JA, Furumoto-Dawson A, Hankin JR, DeGraffinreid C. Advancing the Science of Health Disparities Research. Ethnicity and Disease. 17(3): 427-433, 2007. (Ethnicity & Disease)
Lai CQ, Tucker KL, Parnell LD, Adiconis X, Garcia-Bailo B, Meydani M, Ordovás J. PPARGC1A variation associated with DNA damage, diabetes, and cardiovascular diseases: the Boston Puerto Rican Health Study. Diabetes. Apr 2008;57(4):809-816. PMCID: PMC2519884 (PubMed)
Warnecke RB, Oh A, Breen N, et al. Approaching health disparities from a population perspective: the National Institutes of Health Centers for Population Health and Health Disparities. Am J Public Health 2008;98:1608-15. (PubMed)
Djuric, Z., Bird, C.E., Furumoto-Dawson, A., Rauscher, G.H., Ruffin, M.T., Stowe, R.P., Tucker, K., Masi, C.M. 2008. Biomarkers of psychological stress in health disparities research. The Open Biomarkers Journal. 2008;1:7-19. PMCID: PMC2841407 (PubMed Central)
Smith CE, Tucker KL, Yiannakouris N, Garcia-Bailo B, Mattei J, Lai CQ, Parnell LD, Ordovás JM. Perilipin polymorphism interacts with dietary carbohydrates to modulate anthropometric traits in hispanics of Caribbean origin. J Nutr. Oct 2008;138(10):1852-1858. PMCID: PMC2596596 (PubMed)
Paskett ED, Reeves KW, McLaughlin JM, Katz ML, McAlearney AS, Ruffin MT, Halbert CH, Merete C, Davis F, Gehlert S. Recruitment of minority and underserved populations in the United States: the Centers for Population Health and Health Disparities experience. Contemp Clin Trials. Nov2008;29(6):847-61. PMCID: PMC2642621 (PubMed)
Orho-Melander M, Melander O, Guiducci C, Perez P, Corella D, Roos C, Rieder MJ, Abecasis G, Tai ES, Arnett DK, Lyssenko V, Saxena R, de Bakker P, Burtt N, Voight B, Hirschorn JN, Tucker KL, Hedner T, Tuomi T, Isomaa B, Eriksson KF, Taskinen MR, Hughes TE, Parnell LD, Lai CQ, Peltonen L, Vartiainen E, Jousilahti P, Salomaa V, Groop L, Altshuler D, Ordovás JM, Kathiresan S. A common missense variant in the glucokinase regulatory protein (GCKR) gene is associated with increased plasma triglyceride but lower fasting glucose levels. Diabetes. 2008; 57(11):3112-21. PMCID: PMC2570409 (PubMed)
DeVos L, Chanson A, Liu Z, Ciappio ED, Parnell LD, Mason JB, Tucker KL, Crott JW. Associations between single nucleotide polymorphisms in folate uptake and metabolizing genes with blood folate, homocysteine, and DNA uracil concentrations. Am J Clin Nutr. 2008 Oct;88(4):1149-58. PMCID: PMC2728423 (PubMed)
Junyent M, Tucker KL, Smith CE, Garcia-Rios A, Mattei J, Lai CQ, Parnell LD, Ordovas JM. The effects of ABCG5/G8 polymorphisms on plasma HDL cholesterol concentrations depend on smoking habit in the Boston Puerto Rican health study. J Lipid Res. 2009;50:565-573. PMCID: PMC2638110 (PubMed)
Perez-Martinez P, Corella D, Shen J, Arnett DK, Yiannakouris N, Tai ES, Orho-Melander M, Tucker KL, Tsai M, Straka RJ, Province M, Kai CS, Perez-Jimenez F, Lai CQ, Lopez-Miranda J, Guillen M, Parnell LD, Borecki I, Kathiresan S, Ordovas JM. Association between glucokinase regulatory protein (GCKR) and apolipoprotein A5 (APOA5) gene polymorphisms and triacylglycerol concentrations in fasting, postprandial, and fenofibrate-treated states. Am J Clin Nutr. Jan 2009;89(1):391-9. PMCID: PMC2647710 (PubMed)
Lai CQ, Tucker KL, Choudhry S, Parnell LD, Mattei J, García-Bailo B, Beckman K, Burchard EG, Ordovás JM. Population admixture associated with disease prevalence in the Boston Puerto Rican health study. Hum Genet. 2009 Mar;125(2):199-209. PMCID: PMC2727756 (PubMed)
Lai CQ, Parnell LD, Garcia-Bailo B, Tucker KL, Ordovás J. WDTC1, the ortholog of Drosophila adipose gene, associates with human obesity, modulated by MUFA intake. Obesity 2009;17:593-600. PMCID: PMC2874970 (PubMed)
Gao X, Scott T, Falcon LM, Wilde PE, Tucker KL. Food insecurity and cognitive function in Puerto Rican adults. Am J Clin Nutr, Apr 2009; 89: 1197-1203. PMCID: PMC2667463 (PubMed)
Chanson A, Parnell LD, Ciappio ED, Liu Z, Crott JW, Tucker KL, Mason JB. Polymorphisms in uracil-processing genes, but not one-carbon nutrients, are associated with altered DNA uracil concentrations in an urban Puerto Rican population. Am J Clin Nutr 2009; 89(6):1927-36. PMCID: PMC2683003 (PubMed)
Smith CE, Tucker KL, Scott TM, Van Rompay M, Mattei J, Lai C-Q, Parnell LD, Junyent M, Lee Y-C, Barcia-Bailo B, Ordovás JM. Apolipoprotein C3 polymorphisms, cognition and diabetes in Caribbean origin Hispanics. PLoS ONE. 2009 4(5): e5465. PMCID: PMC2674932 (PubMed)
Noel SE, Newby PK, Ordovás JM, Tucker KL. A traditional rice and beans pattern is associated with metabolic syndrome in Puerto Rican older adults. J Nutr 2009;139: 1360–1367. PMCID: PMC2696989 (PubMed)
Mattei J, Parnell LD, Lai C-Q, Garcia-Bailo B, Adiconis X, Shen J, Arnett D, Demissie-Banjaw S, Tucker KL, Ordovás JM. Disparities in allele frequencies and population differentiation for 101 single nucleotide polymorphisms between Puerto Rican and US-non-Hispanic white older adults. BMC Genetics 2009;10:45. PMCID: PMC2734553 (PubMed)
Smith CE, Tucker KL, Lai C-Q, Parnell LD , Lee Y-C , Ordovás JM. Apolipoprotein A5 and lipoprotein lipase interact to modulate anthropometric measures in Hispanics of Caribbean origin. Obesity 2010;18(2):327-332. PMCID: PMC2813926 (PubMed)
Junyent M, Tucker KL, Smith CE, Lane JM, Mattei J, Lai C-Q, Parnell LD, Ordovás JM. The effects of ABCG5/G8 polymorphisms on HDL cholesterol concentrations depend on ABCA1 genetic variants in the Boston Puerto Rican Health Study. Nutr Metab Cardiovasc Dis 2010;20(8):558-66. PMC Journal – In process (PubMed)
Junyent M, Tucker KL, Shen J, Lee Y-C, Smith CE, Mattei J, Lai C-Q, Parnell LD, Ordovás JM. A composite scoring of genotypes discriminates coronary heart disease risk beyond conventional risk factors in the Boston Puerto Rican Health Study. Nutr Metab Cardiovasc Dis 2010;20(3):157-64. PMC Journal – In process (PubMed)
Mattei J, Demissie S, Tucker KL, Ordovás JM. Apolipoprotein A5 polymorphisms interact with total dietary fat intake in association with markers of metabolic syndrome in Puerto Rican older adults. J Nutr 2009;139:2301-2308. PMCID: PMC2777477 (PubMed)
Falcón LM, Todorova I, Tucker K. Social support, life events, and psychological distress among the Puerto Rican population in the Boston area of the United States. Aging & Mental Health 2009;13:863-873. (PubMed)
Shen J, Lai CQ, Mattei J, Crott JQ,Ordovas JM, Tucker KL. Association of vitamin B6 status with inflammation, oxidative stress and chronic inflammatory conditions: the Boston Puerto Rican Health Study. Am J Clin Nutr 2010;91(2):337-342. PMCID: PMC2806890 (PubMed)
Corella D, Peloso G, Arnett DK, Demissie S, Cupples LA, Tucker K, Lai CQ, Parnell LD, Coltell O, Lee YC, Ordovas JM. APOA2, dietary fat, and body mass index: replication of a gene-diet interaction in 3 independent populations. Arch Intern Med. 2009;169(20):1897-1906. PMCID: PMC2874956 (PubMed)
Rioux CL, Tucker KL, Mwamburi M, Gute DM, Cohen SA, Brugge D. Residential traffic exposure, pulse pressure and C-reactive protein: consistency and contrast among exposure characterization methods. Environ Health Perspect 2010;118(6):803-11. PMCID: PMC2898857 (PubMed)
Rodríguez-Galán MB, Falcón, LM. Patterns of social activity engagement among older Hispanics and their relationship to sociodemographic and health variables. Activities, Adaptation & Aging. 2010;34(4):251-75. (Link to Activities, Adaptation & Aging)
Noel S, Lai C, Ordovás JM, Tucker KL. Variants of the CD36 gene and metabolic syndrome in Boston Puerto Rican adults. Atherosclerosis. 2010;211:210–215. PMCID: PMC2923842 (PubMed)
Mattei J, Demissie S, Falcon LM, Ordovas JM, Tucker KL. Allostatic load is associated with chronic conditions in the Boston Puerto Rican Health Study. Soc Sci Med. 2010; 70(12):1988-96. PMCID: PMC2907654 (PubMed)
Tucker KL, Mattei J, Noel SE, Collado BM, Mendez J, Nelson J, Griffith J, Ordovas, JM, Falcon LM. The Boston Puerto Rican Health Study, a longitudinal cohort study on health disparities in Puerto Rican adults: challenges and opportunities. BMC Pub Health. 2010;10:107. PMCID: PMC2848197 (PubMed)
Castaneda-Sceppa C, Price L, Noel SE, Bassett Midle J, Falcón LM, Tucker KL. Physical function and health status in aging Puerto Rican adults: The Boston Puerto Rican Health Study. J Aging Health. 2010;22(5):653-72. (PubMed)
Noel S, Newby PK, Ordovás JM, Tucker KL. Adherence to an (n-3) Fatty acid/fish intake pattern is inversely associated with metabolic syndrome among Puerto Rican adults in the greater Boston area. J Nutr. 2010;140:1846-54. PMCID: PMC2937577 (PubMed)
Gao X, Lai CQ, Scott T, Shen J, Cai T, Ordovas JM, Tucker KL. Urinary 8-hydroxy-2-deoxyguanosine and cognitive function in Puerto Rican adults. Am J Epidem. 2010;172(3):271-8. PMCID: PMC3026653 (PubMed)
Todorova I, Falcón LM, Lincoln A, Price LL. Perceived discrimination, psychological distress and health. Sociol Health Illn. 2010;32(6):843-61. (PubMed)
Ye X, Maras JE, Bakun P, Tucker KL. Dietary intake of vitamin B6, plasma pyridoxal 5’-phosphate and homocysteine in the Boston Puerto Rican Health Study. J Am Dietet Assoc. 2010;110(11):1660-8. PMCID: PMC2989853 (PubMed)
Lai CQ, Parnell LD, Troen AM, Shen J, Caouette H, Warodomwichit D, Lee YC, Crott JW, Qiu WQ, Rosenberg IH, Tucker KL, Ordovás JM. MAT1A variation are associated with hypertension, stroke, markers of DNA damage and are modulated by plasma vitamin B-6 and folate. Am J Clin Nutr. 2010;91:1377-86. PMCID: PMC2854908 (PubMed)
Bhupathiraju SN, Tucker KL. Greater variety in fruit and vegetable intake is associated with lower inflammation in Puerto Rican adults. Am J Clin Nutr. 2011;93:37-46. PMCID: PMC3001597 (PubMed)
Mattei J, Demissie S, Tucker KL, Ordovas JM. The APOA1/C3/A4/A5 cluster and markers of allostatic load in the Boston Puerto Rican Health Study. Nutr Metab Cardiovasc Dis. 2011;21(11):862-70. PMCID: PMC3004022 (PubMed)
Laugero KD, Falcon LM, Tucker KL. Relationship between perceived stress and dietary and activity patterns in older adults participating in the Boston Puerto Rican Health Study. Appetite. 2011;56(1):194-204. (PubMed)
Rioux CL, Tucker KL, Brugge D, Gute DM, Mwamburi M. Traffic exposure in a population with high prevalence type 2 diabetes – Do medications influence concentrations of C-reactive protein? Environ Pollut. 2011;159(8-9):2051-60. PMCID: PMC3412137 (PubMed)
Huang T, Tucker KL, Lee YC, Crott JW, Parnell LD, Shen J, Smith CE, Ordovas JM, Li D, Lai CQ. Methylenetetrahydrofolate reductase variants associated with hypertension and cardiovascular disease interact with dietary polyunsaturated Fatty acids to modulate plasma homocysteine in Puerto Rican adults. J Nutr. 2011;141(4):654-9. PMCID: PMC3056580 (PubMed)
Henkin S, Tucker KL, Gao X, Falcon LM, Qawi I, Brugge D. Association of depression, psycho-social stress and acculturation with respiratory disease among Puerto Rican adults in Massachusetts. J Immigr Minor Health. 2011:13(2):214-23. (PubMed)
Van Rompay MI, Castaneda-Sceppa C, McKeown NM, Ordovás JM, Tucker KL. Prevalence of cardiovascular disease risk factors among older Puerto Rican adults living in Massachusetts. J Immigr Minor Health. 2011;13(5):825-33. (PubMed)
Ye X, Lai CQ, Crott JW, Troen AM, Ordovas JM, Tucker KL. The folate hydrolase 1561C>T polymorphism is associated with depressive symptoms in Puerto Rican adults. Psychosom Med. 2011 Jun;73(5):385-92. PMCID: PMC3110520. (PubMed)
Huang T, Tucker KL, Lee YC, Crott JW, Parnell LD, Shen J, Smith CE, Ordovas JM, Li D, Lai CQ. Interactions between genetic variants of folate metabolism genes and lifestyle affect plasma homocysteine concentrations in the Boston Puerto Rican population. Public Health Nutr. 2011 Oct;14(10):1805-12. (PubMed)
Ye X, Gao X, Scott T, Tucker KL. Habitual sugar intake and cognitive function among middle-aged and older Puerto Ricans without diabetes. Br J Nutr. 2011;106:1423-32. (PubMed)
Bhupathiraju SN, Lichtenstein AH, Dawson-Hughes B, Tucker KL. Adherence index based on the AHA 2006 diet and lifestyle recommendations is associated with select cardiovascular disease risk factors in older Puerto Ricans. J Nutr. 2011 Mar;141(3):460-9. PMCID: PMC3040903 (PubMed)
Oxenkrug G, Tucker KL, Requintina P, Summergrad P. Neopterin, a marker of interferon-gamma-inducible inflammation, correlates with pyridoxal-5′-phosphate, waist circumference, HDL-cholesterol, insulin resistance and mortality risk in adult Boston community dwellers of Puerto Rican origin. Am J Neuroprotection Neuroregeneration 2011;3:48-52. (Abstract)
Mattei J, Noel SE, Tucker KL. A meat, processed meat, and french fries dietary pattern is associated with high allostatic load in Puerto Rican older adults. J Am Diet Assoc. 2011 Oct;111(10):1498-506. PMCID: PMC3185297 (PubMed)
Corella D, Arnett DK, Tucker KL, Kabagambe EK, Tsai M, Parnell LD, Lai CQ, Lee YC, Warodomwichit D, Hopkins PN, Ordovas JM. A high intake of saturated fatty acids strengthens the association between the fat mass and obesity-associated gene and BMI. J Nutr. 2011 doi:10.3945/jn.111.143826 [Epub ahead of print] (PubMed)
Huang T, Tucker K, Lee Y, Crott J, Parnell L, Shen J, Smith C, Ordovas J, Li D, Lai C. MAT1A variants modulate the effect of dietary fatty acids on plasma homocysteine concentrations. Nutr Metab Cardiovasc Dis. 2012 Apr;22(4):362-8. PMCID: PMC3117050 (PubMed)
VanRompay MI, McKeown NM, Castaneda-Sceppa C, Falcon, LM, Ordovás JM, Tucker KL. Acculturation and sociocultural influences on dietary intake and health status among Puerto Rican adults in Massachusetts. J Acad Nutr Diet 2012;112:64-74. (PubMed)
Perez NA, Weathers B, Willis M, Mendez J. Collaboration across eight research centers: unanticipated benefits and outcomes for project managers. Popul Health Manag. 2013;16(1):46-52. (PubMed)
Feng X, Tucker KL, Parnell LD, Shen J, Lee YC, Ordovás JM, Ling WH, Lai CQ. Insulin receptor substrate 1 (IRS1) variants confer risk of diabetes in the Boston Puerto Rican Health Study. Asia Pac J Clin Nutr. 2013;22(1):150-9. (PubMed)
Ye X, Scott T, Gao X, Maras JE, Bakun PJ, Tucker KL. Mediterranean diet, healthy eating index 2005, and cognitive function in middle-aged and older Puerto Rican adults. J Acad Nutr Diet. 2013 Feb;113(2):276-281. (PubMed)
Moorthy D, Peter I, Scott TM, Parnell LD, Lai CQ, Crott JW, Ordovás JM, Selhub J, Griffith J, Rosenberg IH, Tucker KL, Troen AM. Status of vitamins B-12 and B-6 but not of folate, homocysteine, and the methylenetetrahydrofolate reductase C677T polymorphism are associated with impaired cognition and depression in adults. J Nutr. 2012 Aug;142(8):1554-60. PMCID: PMC3397340 (PubMed)
Ye X, Bhupathiraju SN, Tucker KL. Variety in fruit and vegetable intake and cognitive function in middle-aged and older Puerto Rican adults. Br J Nutr. 2012 May 1:1-8. DOI: 10.1017/S0007114512001183 [Epub ahead of print] (PubMed)
Smith CE, Tucker KL, Lee YC, Lai CQ, Parnell LD, Ordovas JM. Low density lipoprotein receptor related protein 1 variant interacts with saturated fatty acids in Puerto Ricans. Obesity. 2013 Mar;21(3):602-8. (PubMed)
Ma X-Y, Qiu WQ, Smith CE, Parnell LD, Jiang Z-Y, Ordovás JM, Tucker KL, Lai C-Q. Association between BDNF- rs6265 and obesity in the Boston Puerto Rican Health Study. J Obes doi: 10.1155/2012/102942 [Epub ahead of print] PMCID: PMC3543800 (PubMed)
Van Rompay MI, McKeown NM, Sceppa C, Ordovás JM, Tucker KL. Carbohydrate nutrition differs by diabetes status and is associated with dyslipidemia in Boston Puerto Rican adults without diabetes. J Nutr 2013;143:182-8. PMCID: PMC3542909 (PubMed)
Todorova I, Tucker KL, Pescador Jimenez M, Lincoln A, Arevelo S, Falcon LM. Determinants of self-rated health and the role of acculturation: implications for health inequalities. Ethnicity & Health. doi: 10.1080/13557858.2013.771147 [Epub ahead of print] (PubMed)
Zheng J-S, Arnett D, Parnell LD, Lee Y-C, Ma Y, Smith CE, Richardson K, Li D, Borecki IB, Ordovas JM, Tucker KL, Lai C-Q. Genetic variants at PSMD3 interact with dietary fat and carbohydrate to modulate insulin resistance. J Nutr 2013;143:354-61. (PubMed)
Zheng J-S, Arnett DK, Parnell LD, Smith CE, Li D, Borecki IB, Tucker KL, Ordovas JM, Lai-C-Q. Modulation by dietary fat and carbohydrate of IRS1 association with type 2 diabetes traits in two populations of different ancestries. Diab Care 2013; doi: 10.2337/dc12-2607 [Epub ahead of print] (PubMed)

Our previous Massachusetts Hispanic Elders Study (MAHES) study

MAHES publications

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