After eight years of work, a new paper by professor Jonathan Tilly, a reproductive and stem cell biologist, “puts the final nail in the dogma coffin,” toppling a long-held belief about female fertility and ovarian aging. His findings confirm that female mammals make new eggs during adult life, that ovarian stem cells are critical to the process, and that the newly formed eggs contribute directly to maintenance of ovarian function and to natural fertility.
Jonathan Tilly’s infertility research has led to the birth of a baby born with an assist from stem cells. Tilly is the chair of the Department of Biology.
Ellie Shin, SSH/S’16, was determined to work on co-op in a campus research lab. She found one, and has quickly made the most of her experiences.
In 2012, Jonathan Tilly’s team published research in which it identified that certain cells in adult human ovaries produce viable new eggs.