John R. Engen

John Engen

PhD, Analytical Chemistry, University of Nebraska-Lincoln, 1999
BS, Biochemistry, Union College, 1995
BS, Molecular Biology, Union College, 1994

Area(s) of Expertise

Bioanalytical Chemistry and Mass Spectrometry

Research Interests

Current research projects in his laboratory include (1) investigations of kinase conformation to understand regulation and aberrant signaling in various disease states including cancer, (2) analysis of the conformation of viral accessory proteins from HIV, (3) studies of protein conformation at biological membranes, and (4) optimization and methods development in hydrogen exchange mass spectrometry.

Lab Website




423 The Fenway

John R. Engen named College of Science Distinguished Professor

The College of Science Distinguished Professor rank is reserved for the most outstanding faculty in the college. During Engen’s time at Northeastern, he has made a deep and lasting impact on the college’s mission and success.

Studying a critical HIV protein

Professor John Engen helped develop a new hybrid technique to study how a critical HIV protein changes shape to allow infected cells to evade the immune system.