John Engen

Professor Email: Phone: 617.373.6046


Ph.D., Analytical Chemistry, University of Nebraska-Lincoln, 1999
B.S., Biochemistry, Union College, 1995
B.S., Molecular Biology, Union College, 1994

Area(s) of Expertise

Bioanalytical Chemistry and Mass Spectrometry

Research Interests

Current research projects in his laboratory include (1) investigations of kinase conformation to understand regulation and aberrant signaling in various disease states including cancer, (2) analysis of the conformation of viral accessory proteins from HIV, (3) studies of protein conformation at biological membranes, and (4) optimization and methods development in hydrogen exchange mass spectrometry.

Lab Website




423 The Fenway

3Qs: Drug diagnosis

Chemistry and chemical biology professor John R. Engen uses a novel technique to analyze large, complex biopharmaceutical drugs, which could have major implications for healthcare and its associated costs.

Chemistry student awarded Provost’s Research Award

Justin Roberts, an undergraduate student in John Engen’s lab, has been awarded a 2013/14 Provost Undergraduate Research Award.

Undergraduate chemistry student awarded university grant

Congratulations to Kristian Teichert!