Project #1
Combination Anticancer Nanopreparations of Novel Proapoptotic Drug and siRNA
Vladimir P. Torchilin, PhD, DSc (PD/PI)
Scientific Principal Investigator
Distinguished Professor, Dep. of Pharmaceutical Sciences , Director of Center for Pharmaceutical Biotechnology and Nanomedicine (CPBN), Northeastern University
Website
Alexei Degterev, PhD
Co-investigator
Assistant Professor, Tufts University School of Medicine
Website
Project #2
Combined Cancer Therapy with RF Ablation and Drug-Loaded Nanopreparations
S. Nahum Goldberg, MD
Clinical Principal Investigator
Director of Minimally Invasive Tumor Therapy Laboratory Beth Israel Deaconess Medical Center and Associate Professor of Radiology, Harvard Medical School
Website
Muneeb Ahmed, MD
Co-Investigator
Staff Radiologist, Interventional Radiology, Beth Israel Deaconess Medical Center , Assistant Professor of Radiology, Harvard Medical School Associate Director, Minimally Invasive Tumor Therapies Laboratory
Website
Robert Lenkinski, PhD
Co-Investigator
Professor, Department of Radiology, Harvard Medical School, Associate Chief, Radiology, Beth Israel Deaconess Medical Center
Beth Israel Deaconess Medical Center Website
Dana-Farber/Harvard Cancer Center Website
Project #3
Multi-Modal Gene Therapy for Pancreatic Cancer Using Targeted Nanovectors
Mansoor M. Amiji, PhD
Leader
Distinguished Professor and Chair, Department of Pharmaceutical Sciences, School of Pharmacy, Northeastern University, Boston, MA
Website
Rebecca Carrier, PhD
Co-Investigator
Assistant Professor, Department of Chemical Engineering, College of Engineering, Northeastern University, Boston, MA
Website
Edward Whang, MD, PhD
Co-Investigator
Associate Professor of Surgery, Division of General and Gastrointestinal Surgery, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA
Website
Project #4
Development and High Throughput Screening of Targeted Anticancer Nanomedicines
Valery Petrenko, PhD, DSc
Leader
Professor Department of Pathobiology, College of Veterinary Medicine, Auburn University
Website
Deepa Bedi, MD, PhD
Co-Investigator
Research Fellow I, Department of Pathobiology, College of Veterinary Medicine, Auburn University
Core A:
Physico-Chemical Nanocharacterization (PCNC)
Srinivas Sridhar, PhD
Core Leader
Arts and Sciences Distinguished Professor of Physics, Director, Northeastern University, IGERT Nanomedicine Science and Technology NCI/NSF Program, Director, EMR Institute
Physics Website
Sridhar Laboratory Website
Core B:
Imaging
Craig Ferris, PhD
Core Leader
Professor, Director, Center for Translational Imaging Bouve College of Health Sciences, Northeastern University
Psychology Website
CTNI Website
Core C:
Scaling up and Manufacturing
Tim Coleman, PhD
Core Leader:
Chief Executive Officer and President Founder Nemucore Medical Innovations, Inc.
Website
Core D:
The Education and Outreach Activities
Mansoor M. Amiji, PhD
Core Leader
Distinguished Professor and Chair, Department of Pharmaceutical Sciences, School of Pharmacy, Northeastern University, Boston, MA
Website
Pilot Projects:
Pilot Project #1: Lipid-Modified Polyethyleneimine: A Versatite Platform for Enhanced Gene Delivery and siRNA-Mediated Silencing
Dr. Rupa Sawant
Leader
Associate Research Scientist, Department of Pharmaceutical Sciences, Center for Pharmaceutical Biotechnology and Nanomedicine (CPBN), Northeastern University
Website
Pilot Project #2: Alternative Micelle-Like Nanoparticles for Co-Loading of siRNA and Poorly Soluble Drugs
Dr. Gemma Navarro
Leader
Postdoctoral Research Associate, Department of Pharmaceutical Sciences, Center for Pharmaceutical Biotechnology and Nanomedicine (CPBN), Northeastern University
Website
Pilot Project #3: Alternative Modifying RF ablation-induced upregulation of Interleukin-6 using nanocarrier-based anti-IL6 siRNA
Dr. Muneeb Ahmed
Leader
Assistant Professor of Radiology, Harvard Medical School Section of Interventional Radiology, Beth Israel Deaconess Medical Center
Website
