John L. Griffith
Associate Dean of Research, Clinical Professor
Department: Office of Research
Department 2: Department of Health Sciences
Office: 110 Behrakis Health Sciences Center
 
Résumé/CV

Phone: 617-373-7516
Fax: 617-373-6446
Email: jo.griffith@neu.edu

 
 

Education/degrees:  
PhD, Boston University
MS, Tufts University
BA, Claremont Men's College

 Research Interests:
Research focus includes the construction and validation of statistical prediction models for medical decision making, analysis of complex survey designs, and clinical trials.

 Courses:
Associate Director for the Clinical and Translational Graduate Program at Tufts and taught courses there and at the Tufts School of Nutrition including Biostatistics II (CRES 535),  Statistical Methods for Epidemiology (Nutr 318), Predictive Models for Health Outcomes (CRES 510), and Introduction to Clinical Care Research (CRES 525).

 Publications:

1. Pozen MW, D'Agostino RB, Selker HP, Griffith JL.  Tables for using a predictive instrument for acute ischemic heart disease.  Distributed to physicians.
2. Selker HP, Griffith JL, Dorey FJ, D'Agostino RB. How do physicians adapt when the coronary care unit is full? A prospective multicenter clinical trial. JAMA, 257:1181-85, 1987.
3. Griffith JL, Selker HP, Beshansky JR, MacLeod BG.  Cardiac Severity System Software.  Prepared with support of the Robert Wood Johnson Foundation, 1989.
4. Selker HP, Griffith JL, D'Agostino RB. A tool for judging coronary care unit admission appropriateness valid for both real-time and retrospective use: A time-insensitive predictive instrument (TIPI) for acute cardiac ischemia: A multicenter study. Med Care, 29:610-627, 1991.
5. Selker HP, Griffith JL, D'Agostino RB. A time-insensitive predictive instrument for acute myocardial infarction mortality: A multicenter study. Med Care, 29:1196-1211, 1991.
6. Snydman DR, Werner BG, Tilney NL, Kirkman RL, Milford EL, Cho SI, Bush HL, Levey AS, Strom TB, Carpenter CB, Berardi VP, Levey RH, Harmon WE, Zimmerman CE, Katz A, Heinze-Lacey B, Shapiro ME, Steinman T, LoGerfo F, Idelson B, McIver J, Leszczynski J, Griffith JL, Grady GF. Final analysis of primary cytomegalovirus disease prevention in renal transplant recipients with a cytomegalovirus-immune globulin: comparison of the randomized and open-label trials. Transplantation Proceedings, 23:1357-60, 1991.
7. Georgeson S, Linzer M, Griffith JL, Weld L, Selker HP.  Acute cardiac ischemia in patients with syncope: Importance of the initial electrocardiogram. J Gen Int Med, 7:379-386, 1992.
8. Selker HP, Griffith JL, Beshansky JR, Califf RM, D'Agostino RB, Laks MM, Lee KL Maynard C, Wagner GS, Weaver WD.  The Thrombolytic Predictive Instrument (TPI) Project:  Combining clinical study databases to take medical effectiveness research to the streets.  AHCPR DHHS, USA,9-31, 1992.
9. Long WJ, Griffith JL, Selker HP, D'Agostino RB.  A comparison of logistic regression to decision tree induction in a medical domain.  Comput Biomed Res, 26:74-97, 1993.
10. Snydman DR, Werner BG, Dougherty NN, Griffith JL, Rubin RH, Dienstag JL, Rohrer RH, Freeman R, Jenkins R, Lewis D, Hammer S, O'Rourke E, Grady G, Fawaz K, Kaplan MM, Hoffman MA, Katz AT, Doran M.  Cytomegalovirus immune prophylaxis in liver transplantation: a randomized, double-blind, placebo-controlled trial.  Ann Intern Med, 119:984-991, 1993.
11. George MJ, Snydman DR, Werner BG, Dougherty NN, Griffith JL, Rohrer RH, Freeman R, Jenkins R, Lewis WD.  Use of ganciclovir plus cytomegalovirus immune globulin to treat CMV pneumonia in orthotopic liver transplant recipients.  Trans Proc, 25:22-24, 1993.
12. Griffith JL.  Maximum likelihood estimates for feed forward multi-layer neural networks.  PhD dissertation, Boston University, 1994.
13. Larsen GC, Griffith JL, Beshansky JR, D'Agostino RB, Selker HP.  Electrocardiographic left ventricular hypertrophy in patients with suspected acute cardiac ischemia:  its influence on diagnosis, triage and short-term prognosis.  A multicenter study.  J Gen Intern Med, 9:666-673, 1994. [PMID: 7876948]
14. Sarasin FP, Reymond JM, Griffith JL, Beshansky JR, Schifferli JA, Unger PF, Scherrer JR, Selker HP.  Impact of the acute cardiac ischemia time-insensitive predictive instrument (ACI-TIPI) on the speed of triage decision making for emergency department patients presenting with chest pain: a controlled clinical trial.  J Gen Intern Med, 9;187-194, 1994.
15. Selker HP, Beshansky JR, Schmid CS, Griffith JL, Longstreth WT, O'Connor CM, Caplan LR, Massey EW, D'Agostino RB, Laks MM, Lee KL, Maynard C, Wagner GS, Weaver WD, Califf RM.  Presenting pulse pressure predicts thrombolytic therapy-related intracranial hemorrhage: thrombolytic predictive instrument (TPI) project results.  Circulation, 90:1657-1661, 1994.
16. Selker HP, Griffith JL, D'Agostino RB. A time-insensitive predictive instrument for acute mortality due to congestive heart failure: development, testing, and use for comparing hospitals.  A multi-center study.  Med Care, 32:1040-1052, 1994.
17. Snydman DR, Werner BG, Dougherty NN, Griffith JL, Rohrer RH, Freeman R, Jenkins R. Lewis WD O'Rourke E, and the Boston Center for Liver Transplantation CMVIG-Study Group.  A further analysis of the use of cytomegalovirus immune globulin in orthoptic liver transplant patients at risk for primary infection.  Trans Proc, 26:23-27, 1994.
18. Udelson JE, Coleman PS, Metherall J, Pandian NG, Gomez AR, Griffith JL, Shea NL, Oates E, Konstam MA.  Predicting recovery of severe regional ventricular dysfunction: comparison of resting scintigraphy with thallium201 and technetium99-sestamibi.  Circulation, 89:2552-2561, 1994.
19. Chuttani K, Metherall J, Griffith J, Oates E, Konstam MA, Pauker SG, Salem DM, Udelson JE.  Enhanced hepatic uptake of thallium-210 in patients with severe narrowing of the right coronary artery.  AM J Cardiol, 76:1020-1024, 1995.
20. Maynard C, Selker HP, Beshansky JR, Griffith JL, Schmid CH, Califf RM, D'Agostino RB, Laks MM, Lee KL, Wagner GS, Weaver WD.  The exclusion of women from clinical trials of thrombolytic therapy:  implications for developing the thrombolytic predictive instrument.  Med Decis Making,15:38-43, 1995.
21. Selker, HP, Griffith JL, Patil S, Long WL, D'Agostino RB.  A comparison of the performance of mathematical predictive methods for medical diagnosis: the emergency department presentation of acute cardiac ischemia. J of Investig Med; 43:468-476, 1995.
22. Snydman DR, Werner BG, Meissner HC, Cheeseman SH, Schwab J, Bednarek F, Kennedy JL, Herschel M, Magno A, Levin MJ, Valaes T, Berkman E, McIver J, Leszczynski J, Griffith JL, Grady GF.  Use of cytomegalovirus immune globulin in multiply transfused premature neonates. Pediatr Infect Dis J;14:34-40, 1995.
23. Falagas ME, Snydman DR, George M, Werner B, Ruthazer R, Griffith J, Werner BG, Freeman R, Rohrer R, Freeman R, and the Boston Center for Liver Transplantation CMVIG Study Group. Incidence and predictors of cytomegalovirus pneumonia in orthotopic liver transplant recipients. Transplantation; 61; 1716-1720, 1996.
24. Falagas ME, Snydman DR, Ruthazer R, Griffith J, and the Boston Center for Liver Transplantation CMVIG study group.  Primary cytomegalovirus infection in liver transplant recipients: comparison of infections transmitted via donor organs and via transfusions. Clinical Infectious Diseases; 23; 292-297, 1996.
25. Falagas ME, Snydman DR, Griffith J, Werner BG, and the Boston Center for Liver Transplantation CMVIG study group. Exposure to cytomegalovirus from the donated organ is a risk factor for bacteremia in orthotopic liver transplant recipients.  Clin Infect Diseases; 23;468-74, 1996. [PMID: 8879766]
26. Katz DA, Beshansky JR, Griffith JL, Selker HP.  The need to include empiric clinical data in formulating medical practice guidelines.  JAMA, 276;1568-74, 1996. [PMID: 8918854]
 
27. Kimmelstiel CD, Perrone R, Kilcoyne L, Souhrada J, Udleson J, Smith J, de Bold A, Griffith JL, Konstam MA.  Effects of renal neutral endopeptidase inhibition on sodium excretion, renal hemodynamics and neurohormonal activation in patients with congestive heart failure. Cardiology, 87:46-53, 1996.
28. Maynard C, Beshansky JR, Griffith JL, Selker HP.  The influence of sex on the use of cardiac procedures in patients presenting to the emergency department: A prospective multicenter study. Circulation, 94:93-98, 1996.
29. Midgette AS, Griffith JL, Califf RM, Laks MM, Dietz SB, Beshansky JR, Selker HP.  Prediction of the infarct-related artery in acute myocardial infarction by a scoring system using summary ST-segment and T-wave changes.  Am J Cardiol, 78:389-395, 1996. [PMID: 8752181]
30. Coronado BE, Griffith JL, Beshansky JR, Selker HP.  Hospital mortality in women and men presenting to the emergency department with acute cardiac ischemia: A prospective multicenter study.  J Am Coll Cardiol, 29:1490-1496, 1997.
31. D’Agostino RB Sr., Griffith JL, Schmid CH and Terrin NT (1997). Measures for evaluating model performance. Proceedings of the Biometrics Section, American Statistical Association, 1997.
32. Falagas ME, Snydman DR, Griffith J, Ruthazer R, Werner BG, and the Boston Center for Liver Transplantation CMVIG study group.  Effect of Cytomegalovirus infection on first-year mortality rates among orthotopic liver transplant recipients. Ann Intern Med, 126:275-279, 1997.
33. Falagas ME, Barefoot L, Griffith J, Ruthazer R, Snydman DR.  Risk factors leading to clinical failure in patients with intra-abdominal or skin/soft tissue infections.  Eur. J. Clin. Microbiol. Infect. Dis, 15:913-921, 1997.
34. Falagas ME, Snydman DR, Ruthazer R, Werner BG, Griffith JL and the Boston Center for Liver Transplantation CMVIG Study Group.  Surveillance cultures of blood, urine, and throat specimens are not valuable for predicting cytomegalovirus disease in liver transplant recipients. Clin Infect Dis, 24:824-829, 1997.
35. Falagas ME, Arbo M, Ruthazer R, Griffith J, Werner BG, Rohrer R, Freeman R, Lewis WD, Snydman DR.  Cytomegalovirus disease is associated with increased cost and hospital length of stay among orthotopic liver transplant recipients.  Transplantation 63: 1595-1601, 1997.
36. Falagas ME, Snydman DR, Griffith JL, Werner BG, Freemen R, and the Boston Center for Liver Transplantation CMVIG Study Group.  Clinical and epidemiological predictors of recurrent cytomegalovirus disease in orthotopic liver transplant patients.  Clin Infec Dis 25:314-317, 1997.
37. Falagas ME, Snydman DR, Griffith JL, Ruthazer R, Werner BG, Freemen R, Rohrer R  and the Boston Center for Liver Transplantation CMVIG Study Group.  Cytomegalovirus immune globulin (CMVIG) is associated with increased survival after orthotopic liver transplantation. Clin Trans 11:432-437, 1997.
38. George M, Snydman DR, Werner BG, Griffith JL, Falages ME, Doughery NN, Rubin R, and the Boston Center for Liver Transplantation CMVIG Study Group.  The independent role of cytomegalovirus as a risk factor for invasive fungal disease in orthotopic liver transplant recipients.  Amer J Med 103:106-113, 1997.
39. Griffith JL, Schmid CH, Terrin N and D’Agostino RB Sr. Impact of sample size and outcome prevalence on the predictive performance of logistic regression, classification trees and neural networks. Proceedings of the Biometrics Section, American Statistical Association, 1997.
40. Hayes DL, Wang PJ, Reynolds DW, Estes M, Griffith JL, Steffens RA, Carol GL, Findlay GK, Johnson CM.  Pacemaker interference form hand-held wireless telephones: results of a multi-center study.  NEJM 336:1473-1479, 1997.
41. Link MS, Costeas X, Griffith JL, Colburn CC, Estes M, Wang PJ. High incidence of appropriate implantable cardioverter defibrillator therapy in patients with syncope of unknown etiology. J Am Coll Cardiol, 29:370-375, 1997.
42. Maynard C, Beshansky JR, Griffith JL, Selker HP.  Causes of chest pain and symptoms suggestive of acute cardiac ischemia in African American patients presenting to the emergency department: a multicenter study.  JNMA, 89:665-671, 1997.
43. Schmid CH, D’Agostino RB, Griffith JL, Beshansky JR, Selker HP.  A logistic regression model when some events precede treatment: the effect of thrombolytic therapy for acute myocardial infarction on the risk of cardiac arrest. J Clin Epidemiol, 50:1219-1229, 1997.
44. Schmid CH, Griffith JL, Terrin NT, and D’Agostino RB Sr. Synthesising the treatment of missing data in logistic regression, classification trees and neural networks.  Proceedings of the Biometrics Section, American Statistical Association, 1997.
45. Sege B, Perry C, Stigol L, Cohen L, Cohn L, Griffith J, Cohen M,  Spivak H.  Short-term effectiveness of anticipatory guidance to reduce early childhood risks for subsequent violence. Arch Pediatr Adolesc Med, 151:392-397, 1997.
46. Selker HP, Griffith JL, Beshansky JR, Schmid CH, Califf RM, D’Agostino RB, Laks MM, Lee KL, Maynard C, Selvester RH, Wagner GS, Weaver WD.  Patient-specific predictions of outcomes in myocardial infarction for real-time emergency use: a thrombolytic predictive instrument.  Ann Intern Med, 127: 538-556, 1997
47. Terrin N, Griffith JL, Schmid CH and D’Agostino RB Sr. The impact of outliers and distortions on the predictive performance of logistic regression, classification trees and neural networks. Proceedings of the Biometrics Section, American Statistical Association, 1997.
48. Zucker DR, Griffith JL, Beshansky JR, Selker HP.  Presentations of acute myocardial infarction in men and women.  JGIM, 12:79-87, 1997.
49. Faith MS, Manibay E, Kravitz M, Griffith J, Allison DB.  Relative body weight and self-esteem among African Americans in four nationally representative samples.  Obesity Research, 6: 430-437, 1998. [PMID: 9845233]
50. Falagas ME, Walker AM, Jick H, Ruthazer R, Griffith JL, Snydman DR.  Late incidence of cancer after metronisaxole use: a matched metronisazole use/nonuser study.  Clin Inf. Dis, 26:383-8, 1998. [PMID: 9502459]
51. Falagas ME, Paya C, Ruthazer R, Badley A, Patel R, Wiesner R, Griffith J, Freeman R, Rohrer R, Werner BG, Snydman DR.  Significance of Cytomegalovirus for Long-Term Survival after Orthotopic Liver Transplantation: A Prospective Derivation and Validation Cohort Analysis.  Transplantation, 66: 1020-1028, 1998. [PMID: 9808486]
52. Kulig J, Valentine J, Griffith JL, Ruthazer R.  Predictive model of weapon-carrying among urban high school students. J Adol Health, 22:312-319, 1998. [PMID: 9561463]
53. Picken HA, Zucker DR, Griffith JL, Beshansky JR, Selker HP.  Insurance type and the transportation to emergency departments for patients with acute cardiac ischemia: the ACI-TIPI trial insurance study.  Amer J Managed Care, 4:821-827, 1998. [PMID: 10181068]
54. Pope JH, Ruthazer R, Beshansky JR, Griffith, JL, Selker HP.  Clinical features of emergency department patients presenting with symptoms suggestive of acute cardiac ischemia: A multicenter study.  Journal of Thrombosis and Thrombolysis, 6:63-74, 1998. [PMID: 10751787]
55. Selker HP, Beshansky JR, Griffith JL, Aufderheide TP, Ballin DX, Bernard SA, Crespo SG, Feldman J, Fish SS, Gibler WB, Kiez DA, McNutt RA, Moulton AW, Ornato JP, Podried PJ, Salem DN, Sayre MR, Woolard RH.  The use of the Acute Cardiac Ischemic Time-Insensitive Predictive Instrument (ACI-TIPI) to assist emergency department triage of patients with chest pain or other symptoms suggestive of acute cardiac ischemia: a multicenter controlled clinical trail.  Ann Intern Med, 129:845-855, 1998. [PMID: 9867725]
56. Valentine J, Griffith JL, Ruthazer R, Gottlief B, Keel S.  Strengthening causal inference in adolescent drug prevention studies: methods and findings from a controlled study of the urban youth connection program.  Drugs & Society, 12:127-145, 1998.
57. Valentine J, Gottlieb B, Keel S, Griffith J, Ruthazer R.  Measuring the effectiveness of the urban youth connection: the case for dose-response modeling to demonstrate the impact of an adolescent substance abuse prevention program.  J of Adol Res, 1998.
58. Bonis PA, Tong MJ, Blatt LM, Conrad A, Griffith JL.  A predictive model for the development of hepatocellular carcinoma, liver failure, or liver transplantation for patients presenting to clinic with chronic hepatitis C.  Am J Gastroenterology, 94(6): 1605-1612, 1999. [PMID: 10364032]
59. DesJardin JA, Falagas ME, Ruthazer R, Griffith JL, Wawrose D, Schenkein D, Miller K, Snydman D.  Clinical utility of blood cultures drawn from indwelling central venous catheters in hospitalized patients with cancer.  Annals Intern Med, 131:641-647, 1999. [PMID: 10577325]
60. Link MS, Cesarz CA, Griffith JL, Estes NA 3rd, Wang PJ.  Evaluation of coronary revascularization to prevent tachycardia recurrences in survivors of ventricular fibrillation. Am J Cardiol, 83(6): 960-2, 1999. [PMID: 10190419]
61. Sege R, Stringham P, Short S, Griffith J.  Ten years after: examination of adolescent screening questions that predict future violence-related injury.  J Adol Health, 24:395-402, 1999. [PMID: 10401967]
62. Burns JP, Mitchell C, Outwater KM, Geller M, Griffith JL, Todres I, Truog RD. End-of-life care in the pediatric intensive care unit after the forgoing of life-sustaining treatment. Critical Care Med, 28(8): 3060-3066, 2000. [PMID: 10966296]
63. Feldman JA, Fish SS, Beshansky JR, Griffith JL, Woolard RH, Selker HP.  Acute cardiac ischemia in patients with cocaine-associated complaints: results of a multicenter trial.  Ann Emergency Med, 36(5): 469-476, 2000. [PMID: 11054201]
64. Koc Y, Miller K, Schenkein DP, Griffith JL, Ahktar M, DesJardin J, Snydman DS. Varicella zoster virus infections following allogeneic bone marrow transplantation: Frequency, risk factors, and clinical outcome. Biology of Blood and Marrow Transplantation, 6:44-49, 2000. [PMID: 10707998]
65. Pope JH, Aufderheide TP, Ruthazer R, Woolard RH, Feldman JA, Beshansky JR, Griffith JL, Selker HP. Missed diagnoses of acute cardiac ischemia in the emergency department. N Engl J Med, 342:1163-1170, 2000. [PMID: 10770981]
66. Burns JP, Mitchell C, Griffith JL, Troug RD.  End-of-life care in the pediatric intensive care unit attitudes and practices of pediatric clinical care physicians and nurses.  Crit Care Med, 29(3): 695-696, 2001. [PMID: 11373439]
67. Moskowitz H, Griffith JL, DiScala C, Sege RD.  Serious injuries and deaths of adolescent girls resulting from interpersonal violence: Characteristics and trends from the United States, 1989-1998.  Arch Pediatr Adolesc Med, 155:903-908, 2001. [PMID: 11483117]
68. Finlay GA, Joseph B, Rodrigues CR, Griffith JL, White AC. Advanced Presentation of Lung Cancer in Asian Immigrants: A Case-Control Stud. Chest, 122: 1938-1943, 2002. [PMID: 12475830]
69. Gill CJ, Griffith JL, Jacobson D, Skinner S, Gorbach SL, and Wilson IB.  Relationship of HIV viral loads, CD4 counts, and HAART use to health-related quality of life. JAIDS, 30:485-492, 2002. [PMID: 12154339]
70. Greenfield S, Kaplan SH, Kahn R, Ninomiya J, Griffith JL.  Profiling care provided by different groups of physicians: Effects of patient case-mix (Bias) and physician-level clustering on quality assessment results. Ann Intern Med, 136:111-121, 2002. [PMID: 11790062]
71. Kent DM, Hayward RA, Griffith JL,Vijan S, Beshansky JR, Califf M, Selker HP. Independently derived and validated predictive model for selecting patients with myocardial infarction who are likely to benefit from tissue plasminogen activator compared with streptokinase. Am J Med,113: 104-111, 2002. [PMID: 12133748]
72. Kent DM, Griffith J. The Framingham scores overestimated the risk for coronary heart disease in Japanese, Hispanic, and Native American cohorts. ACP J Club. 136(1): 36. 2002. [PMID: 11829577]
73. Meyer EC, Burns JP, Griffith JL, Truog RD.  Parental perspectives on end-of-life care in the pediatric intensive care unit.  Crit Care Med, 30(1): 226-231, 2002. [PMID: 11902266]
74. Sarnak MJ, Tighuouart H, Manjunath G, MacLeod B, Griffith JL, Salem D, Levey AS.  Anemia as a risk factor for cardiovascular disease in the atherosclerosis risk in communities (aric) study.  Journal of the American College of Cardiology, 40(1):27-33, 2002. [PMID: 12103252]
75. Selker HP, Beshansky JR, Griffith JL, For the TPI Trial Investigators. Use of the electrocardiograph-based thrombolytic predictive instrument to assist thrombolytic and reperfusion therapy for acute myocardial infarction: a multicenter randomized clinical effectiveness trial. Ann Intern Med, 137:87-95, 2002. [PMID: 12118963]
76. Udelson, JE, Beshansky,JR, Ballin,DS, Feldman, JA, Griffith, JL, Heller, GV, Hendel, RC, Pope, JH, Ruthazer, R, Spiegler, EJ, Woolard, RH, Handler, JH, Selker, HP, Myocardial Perfusion Imaging for Evaluation and Triage of Patients With Suspected Acute Cardiac Ischemia, JAMA, 288(21) 2693-2700, 2002. [PMID: 12460092]
77. Manjunath G, Tighiouart H, Ibrahim H, MacLeod B, Salem DN, Griffith JL, Coresh J, Levey AS, Sarnak MJ. Level of kidney function as a risk factor for atherosclerotic cardiovascular outcomes in the community.  J Am Coll Cardiol, 41(1):47-55, 2003. [PMID: 12570944]
78. Manjunath G, Tighiouart H, Coresh J, Macleod B, Salem DN, Griffith JL, Levey AS, Sarnak MJ. Level of kidney function as a risk factor for cardiovascular outcomes in the elderly. Kidney Int. 63(3): 1121-9, 2003. [PMID: 12631096]
79. Selker HP, Raitt MH, Schmid CH, Laks MM, Beshansky JR, Griffith JL, Califf RM, Selvester RH, Maynard C, D'Agostino RB, Weaver WD. Time-dependent predictors of primary cardiac arrest in patients with acute myocardial infarction. Am J Cardiol, 91(3):280-6, 2003. [PMID: 12565083]
80. Terrin N, Schmid CH, Griffith JL, D'Agostino RB, Selker HP.  External validity of predictive models: a comparison of logistic regression, classification trees, and neural networks. J Clin Epidemiol, 56(8): 721-9, 2003. [PMID: 12954463]
81. Amin MG, Tighiouart H, Weiner DE, Stark PC, Griffith JL, MacLeod B, Salem DN, Sarnak MJ. Hematocrit and left ventricular mass: the Framingham Heart study. J Am Coll Cardiol, 43(7): 1276-82, 2004. [PMID: 15063442]
82. Coronado BE, Pope JE, Griffith JL, Beshansky JR, and Selker HP. Clinical features, triage, and outcome of patients presenting to the ED with suspected acute coronary syndromes but without pain: A multicenter study.  The American Journal of Emergency Medicine, 22:568-574, 2004. [PMID: 15666263]
83. Kapetanopoulos A, Heller GV, Selker HP, Ruthazer R, Beshansky JR, Feldman JA, Griffith JL, Hendel RC, Pope JH, Spiegler EJ, Udelson JE. Acute resting myocardial perfusion imaging in patients with diabetes mellitus: results from the Emergency Room Assessment of Sestamibi for Evaluation of Chest Pain (ERASE Chest Pain) trial, J Nucl Cardiol, 11(5):570-577, 2004. [PMID: 15472642]
84. Kent DM, Vijan S, Hayward RA, Griffith JL, Beshansky JR, Selker HP. Tissue plasminogen activator was cost-effective compared to streptokinase in only selected patients with acute myocardial infarction. J Clin Epi, 57(8): 843-852, 2004. [PMID: 15485737]
85. Milch CE, Edmunson JM, Beshansky JR, Griffith JL, Selker HP. Smoking cessation in primary care: a clinical effectiveness trial of two simple interventions. Preventive Medicine, 38(3): 284-294, 2004. [PMID: 14766110]
86. Pope JH, Ruthazer R, Kontos MC, Beshansky JR, Griffith JL, Selker HP.  The Impact of Electrocardiographic Left Ventricular Hypertrophy and Bundle Branch Block on the Triage and Outcome of Emergency Department Patients with a Suspected Acute Coronary Syndrome: A Multicenter Study.  Am J of Emergency Med. 22(3):156-63, 2004. [PMID: 15138949]
87. Scott TM, Tucker KL, Bhadelia A, Benjamin B, Patz S, Bhadelia R, Liebson E, Price LL, Griffith J, Rosenberg I, Folstein MF. Homocysteine and B vitamins relate to brain volume and white-matter changes in geriatric patients with psychiatric disorders. Am J Geriatr Psychiatry, 12(6):631-8, 2004. [PMID: 15545331]
88. Weiner DE, Tighiouart H, Amin MG, Stark PC, MacLeod B, Griffith JL, Salem DN, Levey AS, Sarnak MJ.  Chronic kidney disease as a risk factor for cardiovascular disease and all-cause mortality: a pooled analysis of community-based studies. J Am Soc Nephrol., 15(5):1307-15, 2004. [PMID: 15100371]
89. Weiner D, Tighiouart H, Stark P, Amin M, MacLeod B, Griffith J, Salem D, Levey A, Sarnak M.  Kidney disease as a risk factor for recurrent cardiovascular disease and mortality. Am J Kidney Diseases, 44(2): 198-206, 2004. [PMID: 15264177]
90. Dansinger, ML, Gleason JA, Griffith JL, Selker HP, Schaefer EJ. Comparison of the Atkins, Ornish, Weight Watchers, and Zone Diets for Weight Loss and Heart Disease Risk Reduction: A Randomized Trial. JAMA. 293:43-53, 2005. [PMID: 15632335]
91. Pope JH, Ruthazer R, Kontos MC, Beshansky JB, Griffith JL, Selker HP.  The Impact of electrocardiographic left ventricular hypertrophy and bundle branch block on the triage and outcome of ED patients with a suspected acute coronary syndrome: a multicenter study.  Am J Emerg Med, 22(3): 156-164, 2005. [PMID: 15138949]
92. Vlagopoulos PT, Tighiouart H, Weiner DE, Griffith JL, Pettitt D, Salem DN, Levey AS, Sarnak MJ. Anemia as a risk factor for cardiovascular disease and all-cause mortality in diabetes: the impact of chronic kidney disease. Journal of the American Society of Nephrology, 16(11):3403-10, 2005. [PMID: 16162813]
93. Weiner DE, Tighiouart H, Vlagopoulos PT, Griffith JL, Salem DN, Levey AS, Sarnak MJ.  Effects of anemia and left ventricular hypertrophy on cardiovascular disease in patients with chronic kidney disease. J Am Soc Nephrol. 16:1803-1810, 2005. [PMID: 15857925]
94. Golan Y, Doron S, Griffith J, El Gamal H, Tanios M, Blunt K, Barefoot L, Bloom J, Gamson K, Snydman LK, Hansjosten K, Elnekave E, Nasraway SA, and Snydman DR.  The impact of gown-use requirement on hand hygiene compliance. Clinical Infectious Diseases 42:370-376, 2006. [PMID: 16392083]
95. Scott TM, Peter I, Tucker KL, Arsenault L, Bergethon P, Bhadelia R, Buell J, Collins L, Dashe JF, Griffith J, Hibberd P, Leins D, Liu T, Ordovas JM, Patz S, Price LL, Qiu WQ, Sarnak M, Selhub J, Smaldone L, Wagner C, Wang L, Weiner D, Yee J, Rosenberg I, Folstein M. The Nutrition, Aging, and Memory in Elders (NAME) study: design and methods for a study of micronutrients and cognitive function in a homebound elderly population. Int J Geriatr Psychiatry, 21(6):519-28, 2006. [PMID: 16645938]
96. Weiner DE, Tabatabai S, Tighiouart H, Elsayed E, Bansal N, Griffith J, Salem DN, Levey AS, Sarnak MJ. Cardiovascular outcomes and all-cause mortality: exploring the interaction between CKD and cardiovascular disease. Am J Kidney Dis. 48(3): 392-401. 2006. [PMID: 16931212]
97. Trokel M, Griffith J, Waddimba A, Sege R. Variation in the Diagnosis of Child Abuse in Severely Injured Infants. Pediatrics, 117: 722-728, 2006. [PMID: 16510652]
98. Bansal N, Tighiouart H, Weiner D, Griffith J, Vlagopoulos P, Salem D, Levin A, Sarnak MJ.  Anemia as a Risk Factor for Kidney Function Decline in Individuals with Heart Failure. The American Journal of Cardiology, 99:1137-1142. 2007. [PMID: 17437743]
99. Concannon TW, Kent DM, Normand SL, Newhouse JP, Griffith JL, Ruthazer R, Beshansky JR,  Wong JB, Aversano T, and Selker HP.  A Geospatial Analysis of Emergency Transport and Inter-Hospital Transfer in ST-Segment Elevation Myocardial Infarction.  The American Journal of Cardiology. 101(1):69-74. 2007. [PMID: 18157968]
100. Elsayed EF, Tighiouart H, Griffith J, Kurth T, Levey AS, Salem D, Sarnak MJ, Weiner DE. Cardiovascular disease and subsequent kidney disease, Arch Intern Med. 167(11):1130-6, 2007. [PMID: 17576295]
101. Kent DM,  Ruthazer R, Griffith JL, Beshansky JR, Grines CL, Aversano T, Concannon TW, Zalenski RJ, Selker HP. Comparison of Mortality Benefit of Immediate Thrombolytic Therapy Versus Delayed Primary Angioplasty for Acute Myocardial Infarction. The American Journal of Cardiology, 99:1384-1388, 2007. [PMID: 17576295]
102. Pereira AA, Weiner DE, Scott T, Chandra P, Bluestein R, Griffith JL, Sarnak MJ.  Subcortical Cognitive Impairment in Dialysis Patients.  Hemodialysis International, 11:309-314, 2007. [PMID: 17576295]
103. Vega-Lopez S, Ausman LM, Griffith JL, and Lichtenstein AH. Interindividual Variability and Intra-Individual Reproducibility of Glycemic Index Values for Commercial White Bread. Diabetes Care, 30:1412-1417, 2007. [PMID: 17384339]
104. Weiner DE, Tighiouart H, Levey AS, Elsayed E, Griffith JL, Salem DN, and Sarnak MJ.
Lowest Systolic Blood Pressure Is Associated with Stroke in Stages 3 to 4 Chronic Kidney Disease. J. Am. Soc. Nephrol., 18: 960 – 966, 2007. [PMID: 17301190]
105. Weiner DE, Tighiouart H, Griffith JL, Elsayed E, Levey AS, Salem DN, Sarnak MJ. Kidney Disease, Framingham Risk Scores, and Cardiac and Mortality Outcomes. The American Journal of Medicine (120): 552e.1-8. 2007.[ PMID: 17576295]
106. Weiner DE, Tighiouart H, Elsayed EF, Griffith JL, Salem DN, Levey AS, Sarnak MJ. The Framingham Predictive Instrument in Chronic Kidney Disease. Journal of the American College of Cardiology, 50:217-224. 2007.[ PMID: 17631213]
107. Concannon TW, Kent DM, Normand SL, Newhouse JP, Griffith JL, Ruthazer R, Beshansky JR, Wong JB, Aversano T, Selker HP.  A Geospatial Analysis of Emergency Transport and Inter-Hospital Transfer in ST-Segment Elevation Myocardial Infarction. 101(1): 69-74. 2008. [PMID: 18157968]
108. Elsayed EF, Tighiouart H, Weiner DE, Griffith J, Salem D, Levey AS, Sarnak MJ. Waist-to-hip ratio and body mass index as risk factors for cardiovascular events in CKD. Am J Kidney Dis, 52(1): 49-57. [PMID: 18514990]
109. Elsayed EF, Sarnak MJ, Tighiouart H, Griffith JL, Kurth T, Salem DN, Levey AS, Weiner DE.  Waist-to-Hip Ratio, Body Mass Index, and Subsequent Kidney Disease and Death. American Journal of Kidney Diseases, 52(1): 29-38. 2008. [PMID: 18511168]
110. Flaherty EG, Sege RD, Griffith J, Price LL, Wasserman R, Slora E, Dhepyasuwan N, Harris D, Norton D, Angelilli ML, Abney D, Binns HJ. From suspicion of physical child abuse to reporting: primary care clinician decision-making. Pediatrics, 122(3):611-9: 2008. [PMID: 18676507]
111. Kent DM, Ruthazer R, Griffith JL, Beshansky JR, Concannon TW, Aversano T, Grines CL, Zalenski RJ, Selker HP. A Percutaneous Coronary Intervention–Thrombolytic Predictive Instrument to Assist Choosing Between Immediate Thrombolytic Therapy Versus Delayed Primary Percutaneous Coronary Intervention for Acute Myocardial Infarction. The American Journal of Cardiology. 101(6): 790-795. 2008. [PMID: 18328842]
112. Layne JE, Sampson SE, Mallio CJ, Hibberd PL, Griffith JL, Das SK, Flanagan WJ, Castaneda-Sceppa C. Successful dissemination of a community-based strength training program for older adults by peer and professional leaders: the people exercising program. J Am Geriatrics Soc, 56(12):2323-9, 2008. [PMID: 19112654]
113. Madan J, Fiascone J, Balasubramanian V, Griffith J, Hagadorn JI. Predictors of Ductal Closure and Intestinal Complications in Very Low Birth Weight Infants Treated with Indomethacin. Neonatology, 94:45-51. 2008. [PMID: 18215699]
114. Weiner DE, Tighiouart H, Elsayed EF, Griffith JL, Saleem DN, and Levey AS.  Uric Acid and Incident Kidney Disease in the Community. J Am Soc Nephrol. 19(6):1204-11. 2008. [PMID: 18337481]
115. Weiner DE, Tighiouart H, Elsayed EF, Griffith JL, Salem DN, Levey AS, Sarnak MJ.  The Relationship Between Nontraditional Risk Factors and Outcomes in Individuals With Stage 3 to 4 CKD.  American Journal of Kidney Diseases. 51(2): 212-223. 2008. [PMID: 18215699]
116. Weiner DE, Tighiouart H, Elsayed EF, Griffith JL, Salem DN, Levey AS, Sarnak MJ. Inflammation and cardiovascular events in individuals with and without chronic kidney disease. Kidney Int. 73(12): 1406-12. 2008. [PMID: 18401337]
117. Castaldi PJ, DeMeo DL, Kent DM, Campbell EJ, Barker AF, Brantly ML, Eden E, McElvaney NG, Rennard SI, Stocks JM, Stoller JK, Strange C, Turino G, Sandhaus RA, Griffith JL, Silverman EK. Development of predictive models for airflow obstruction in alpha-1-antitrypsin deficiency. Am J Epidemiol. 170(8):1005-13. 2009 [PMID: 19726494].
118. Concannon TW, Griffith JL, Kent DM, Normand SL, Newhouse JP, Atkins J, and Beshansky JR, Selker HP. Elapsed time in emergency medical services for patients with cardiac complaints: are some patients at greater risk for delay? Circ Cardiovasc Qual Outcomes. 2(1):9-15. 2009 [PMID: 20031807]
119. Gabbay E, Meyer KB, Griffith JL, Richardson MM, Miskulin DC. Temporal trends in health-related quality of life among hemodialysis patients in the United States. Clin J Am Soc Nephrol. 5(2):261-7. 2009 [PMID: 20019114].
120. Kaplan SH, Griffith JL, Price LL, Pawlson LG, Greenfield S. Improving the Reliability of Physician Performance Assessment: Identifying the "Physician Effect" on Quality and Creating Composite Measures. Med Care. 47(4):378-87. 2009. [PMID: 19279511]
121. Weiner DE, Bartolomei K, Scott TM, Price L, Griffith JL, Rosenberg I, Levey AS, Folstein MF, Sarnak MJ.  Albuminuria, Cognitive Functioning, and White Matter Hyperintensities in Homebound Elders. American Journal of Kidney Diseases. 53(3): 438-447. 2009. [PMID: 19070412]
122. Agganis BT, Weiner DE, Giang LM, Scott T, Tighiouart H, Griffith JL, Sarnak MJ. Depression and Cognitive Function in Maintenance Hemodialysis Patients. Am J Kidney Dis. 56(4):704-12. 2010. [PMCID 20673602]
123. Concannon TW, Kent DM, Normand SL, Newhouse JP, Griffith JL, Cohen J, Beshansky JR, Wong JB, Aversano T, Selker HP. Comparative effectiveness of ST-segment-elevation myocardial infarction regionalization strategies. Circ Cardiovasc Qual Outcomes. 3(5):506-13. 2010. [PMID: 20664025]
124. Selker HP, Leslie LK, Wasser JS, Plaut AG, Wilson IB, Griffith JL. Comparative Effectiveness Research as a Conceptual Framework for a Focus on Impact. Clin Transl Sci. 3(2):56-8. 2010. [PMID 20443959]
125. Tucker KL, Mattei J, Noel SE, Collado BM, Mendez J, Nelson J, Griffith J, Ordovas JM, Falcon LM. The Boston Puerto Rican Health Study, a longitudinal cohort study on health disparities in Puerto Rican adults: challenges and opportunities.  BMC Public Health. 10(107): 2010 [PMCID: 2848197]
126. McAlindon TE, Nuite M, Krishnan N, Ruthazer R, Price LL, Burstein D, Griffith J, Flechsenhar K. Change In Knee Osteoarthritis Cartilage Detected By Delayed Gadolinium Enhanced Magnetic Resonance Imaging Following Treatment With Collagen Hydrolysate: A Pilot Randomized Controlled Trial. Osteoarthritis Cartilage. 19(4):399-405. 2011. [PMCID: 21251991]
127. Selker HP, Beshansky JR, Ruthazer R, Sheehan PR, Sayah AJ, Atkins JM, Aufderheide TP, Pirrallo RG, D'Agostino RB, Massaro JM, Griffith JL. Emergency medical service predictive instrument-aided diagnosis and treatment of acute coronary syndromes and ST-segment elevation myocardial infarction in the IMMEDIATE trial. Prehosp Emerg Care. 15(2):139-48. 2011. [PMID: 21366431]
128. Selker HP, Ruthazer R, Terrin N, Griffith JL, Concannon T, Kent DM. Random treatment assignment using mathematical equipoise for comparative effectiveness trials. Clin Transl Sci. 4(1):10-6.  2011. [PMID: 2134895]
129. Selker HP, Beshansky JR, Ruthazer R, Sheehan PR, Sayah AJ, Atkins JM, Aufderheide TP, Pirrallo RG, D'Agostino RB, Massaro JM, Griffith JL. Emergency medical service predictive instrument-aided diagnosis and treatment of acute coronary syndromes and ST-segment elevation myocardial infarction in the IMMEDIATE trial. Prehosp Emerg Care.15(2):139-48. 2011. [PMID: 1366431]
130. Tangri N, Wagner M, Griffith J, Miskulin D, Hodsman A, Ansell D, Naimark D. Effect of Bone Mineral Guideline Target Achievement on Mortality in Incident Dialysis Patients: An Analysis of the United Kingdom Renal Registry. Am J Kidney Dis. 57(3):415-21. 2011. [PMCID: 21131115]
131. Concannon T, Nelson J, Goetz J, Griffith JL. A Percutaneous Coronary Intervention Lab in Every Hospital? Circ Cardiovasc Qual Outcomes 5: 14-20. 2012. [PCMID: 22147882]
132. Moorthy D, Peter  I, Scott TM, Parnell LD, Lai C, Crott JW, Ordovás JM, Selhub J, Griffith J, Rosenberg IH, Tucker KL, Troen AM.  Status of vitamin B-12 and B-6 but not of folate, homocysteine and the methylenetetrahydrofolate reductase C677T polymorphism are associated with impaired cognition and depression in adults. J. Nutr. 142: 1554–1560, 2012. [PMID 22739363]
133. Selker HP, Beshansky JR, Sheehan PR, Massaro JM, Griffith JL, D'Agostino RB, Ruthazer R, Atkins JM, Sayah AJ, Levy MK, et al. Out-of-hospital administration of intravenous glucose-insulin-potassium in patients with suspected acute coronary syndromes: the IMMEDIATE randomized controlled trial. JAMA. 9;307(18):1925-33. 2012 [PMID 22452807]
134. Selker HP, Beshansky JR, Griffith JL, D'Agostino RB, Massaro JM, Udelson JE, Rashba EJ, Ruthazer R, Sheehan PR, Desvigne-Nickens P, et al. Study design for the Immediate Myocardial Metabolic Enhancement During Initial Assessment and Treatment in Emergency Care (IMMEDIATE) Trial: A double-blind randomized controlled trial of intravenous glucose, insulin, and potassium for acute coronary syndromes in emergency medical services. Am Heart J. 163(3):315-22. 2012. [PMID: 22424000]
 


 
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