PhD Programs

The department offers PhD programs in Pharmaceutical Science. Increasingly, scientific work is becoming interdisciplinary. In response to this trend, we allow the student to focus on more than one area in biomedical science. The concept is appropriate for both those entering as well as those currently employed in the field, including research technicians, clinical laboratory workers, science teachers and science administrators. For those currently employed, the flexibility of our program can enhance their performance in a present position or open up new employment opportunities. Graduates of the program will be well prepared to enter related PhD programs at the University.

Department of Pharmaceutical Sciences
PhD in Medicinal Chemistry and Drug Discovery

This specialization offered by the Center for Drug Discovery (CDD) trains students in the design and synthesis of novel biologically active compounds and in the study of their mechanisms of action using biochemical, biophysical and pharmacological approaches. Concentrations are available in: synthetic; biochemical/ pharmacological; and biophysical medicinal chemistry. The CDD’s excellence in teaching has been recognized by the award of a Training Grant from the National Institute on Drug Abuse for predoctoral and postdoctoral training in development of medications. These will be targeted to treat drug abuse, addiction and other indications such as neuropathic pain, obesity, neuropsychiatric disorders (psychoses, ADHD, depression, anxiety, eating disorders) and neurodegenerative disorders.

Doctoral students receive tuition waivers and usually receive stipends for research or teaching of $25,000-$30,000/year.

Center for Drug Discovery

Curriculum

Pharmaceutical Science core courses 5-7 SH
PHSC 5100 Concepts in Pharmaceutical Science 2 SH
PHSC 6210 Drug Design, Evaluation and Development 2 SH
PHSC 6212 Research Skills and Ethics 1 SH or
CHEM 5600 Research Skills and Ethics in Chemistry 3 SH or
BIOL 6381 Ethics in Biological Research 2 SH

Medicinal Chemistry / Drug Discovery Specialization Courses 9 SH

PHSC 6222 Chemistry and Biology of Drugs of Abuse 2 SH
PHSC 6224 Behavioral Pharmacology and Drug Discovery 2 SH
PHSC 6226 Imaging in Medicine and Drug Discovery 2 SH
CHEM 5676 Bioorganic Chemistry 3 SH

General Electives 19-21 SH

Advisor consultation is required when choosing electives

Ph.D. Core – 12 SH minimum
PHSC 6300 Pharmaceutical Science Seminar 1 SH (must be taken more than once)
PHSC 8940 Doctoral Training & Research 1 SH (Qualifying Exam Preparation)
PHSC 9681 Doctoral Proposal 2 SH
PHSC 6810 Pharmaceutical Science Colloquium 1 SH
PHSC 9990 Dissertation 3 SH (must be taken twice)

Total number of credits 45 SH

Specialization-specific non-course requirements
Participation in Journal Club

*Students coming in with a Master’s degree must complete the 12 SH for the PhD core courses and any other courses deemed necessary by the committee members.

PhD in Pharmacology

The PhD pharmacology specialization allows a student to specialize in the study of the actions of drugs. In addition to developing a sound knowledge base through course work and seminars, the program is designed to strengthen the student’s ability to comprehend and to evaluate critically the current literature, allowing the conduct of significant independent research. Recent graduates with a PhD in pharmacology have found employment in academic or industrial research positions.

Doctoral students receive tuition waivers and usually receive stipends for research or teaching of $25,000-$30,000/year.

Curriculum

Pharmaceutical Science Core 5-6SH
PHSC 5100 / Concepts in Pharmaceutical Science / 2 SH
PHSC 6210 / Drug Design, Evaluation and Development / 2 SH
PHSC 6212 / Research Skills and Ethics / 1 SH or
BIOL 6381 / Ethics in Biological Research / 2 SH

Pharmacology Specialization Core 18 SH
PHSC 6214 / Experimental Design and Biometrics / 2 SH
PHSC 6216 / Human Physiology and Pathophysiology / 2 SH
PMCL 6260 / Pharmacology 1 / 2 SH
PMCL 6261 / Pharmacology 2 / 2 SH
PMCL 6262 / Receptor Pharmacology / 2 SH

Students must take either:
BIOL 6300 / Graduate Biochemistry / 4 SH OR
PHSC 5300 / Pharmaceutical Biochemistry / 2 SH AND
BIOL 6301 / Molecular Cell Biology / 4 SH OR
PHSC 5310 / Cellular Physiology / 2 SH

PhD Core – 12 SH minimum
PHSC 6300 / Pharmaceutical Science Seminar / 1 SH / (must be taken more than once)
PHSC 8940 / Doctoral Training & Research / 1 SH / (Qualifying Exam Preparation)
PHSC 9681 / Doctoral Proposal / 2 SH
PHSC 6810 / Pharmaceutical Science Colloquium 1 SH
PHSC 9990 / Dissertation / 3 SH / (must be taken twice)

General Elective Core 10-12 SH
Advisor consultation is required when choosing electives

Common elective courses:

PHSC 6226 / Imaging in Medicince and Drug Discovery / 2SH
PHSC 7010 / PharmSci Lab / 4SH
PHSC 5200 / Advanced Immunology / 2SH
PHSC 6222 / Chemistry and Biology of Drugs of Abuse / 2SH
PHSC 6218 / Biomedical and Chemical Analysis / 2SH
NNMD 7270 / Introduction to Nanomedicine / 3SH
PHSC 6984 / Research / 2SH
PHSC 5976 / Directed Study / 1SH
PHSC 6300 / Seminar (Journal Club) 1SH

Total number of credits 45 SH

*Students coming in with a Master’s degree must complete the 12 SH for the PhD core courses and any other courses deemed necessary by the committee members.

Pharmaceutical Sciences (PhD): Pharmaceutics and Drug Delivery Systems

Students earning a PhD degree in Pharmaceutics and Drug Delivery will be thoroughly versed in the fundamentals of physical pharmacy and pharmaceutics in addition to being trained in several more specialized areas such as:

  • Novel Drug Delivery Systems
  • Nanomedical Technologies
  • Physical Pharmacy
  • Biopharmaceutics and Pharmacokinetics

With exposure to these various facets of pharmaceutics, graduates are poised to understand and assimilate the field of modern pharmaceutics. A PhD in pharmaceutics is a research degree. While course work plays an important role, students become a real participant in the science of pharmaceutics in the laboratory. Faculty research covers a broad range of scientific interests including: pharmacokinetic toxicodynamics of anticancer agents, use of biomaterials and synthetic polymeric systems in design of drug delivery systems, passive and active targeting of therapeutic agents, cardiovascular targeting of drugs, novel delivery systems for proteins and peptides and mathematical modeling of endogenous compounds.

Doctoral students receive tuition waivers and usually receive stipends for research or teaching of $25,000-$30,000/year.

Curriculum

Pharmaceutical Science Core 5-6 SH
PHSC 5100 / Concepts in Pharmaceutical Science / 2 SH
PHSC 6210 / Drug Design, Evaluation and Development / 2 SH
PHSC 6212 / Research Skills and Ethics / 1 SH or
BIOL 6381 / Ethics in Biological Research / 2 SH

Pharmaceutics/Drug Delivery Specialization Core 22 SH
PHSC 6214 / Experimental Design and Biometrics / 2 SH
PHSC 6216 / Human Physiology and Pathophysiology / 2 SH
PHSC 6218 / Biomedical Chemical Analysis / 2 SH
BIOL 6300 / Graduate Biochemistry / 4 SH
BIOL 6301 / Molecular Cell Biology / 4 SH
PMST 6250 / Advanced Physical Pharmacy / 2 SH
PMST 6252 / Pharmacokinetics and Drug Metabolism / 3 SH
PMST 6254 / Advanced Drug Delivery System / 3 SH
Studenst must take either:
BIOL 6300 / Graduate Biochemistry / 4 SH OR
PHSC 5300 / Pharmaceutical Biochemistry / 2 SH AND
BIOL 6301 / Molecular Cell Biology / 4 SH OR
PHSC 5310 / Cellular Physiology / 2 SH

PhD Core – 12 SH minimum
PHSC 6300 Pharmaceutical Science Seminar / 1 SH (must be taken more than once)
PHSC 8940 Doctoral Training & Research 1 SH / (Qualifying Exam Preparation)
PHSC 9681 Doctoral proposal 2 SH
PHSC 6810 Pharmaceutical Science Colloquium 1 SH
PHSC 9990 Dissertation 3 SH / (must be taken twice)

General Elective Core 4-6 SH
Advisor consultation is required when choosing electives

Common elective courses:

PHSC 6226 / Imaging in Medicine and Drug Discovery / 2SH
PHSC 7010 / PharmSci Lab / 4SH
PHSC 5200 / Advanced Immunology / 2SH
PHSC 6222 / Chemistry and Biology of Drugs of Abuse / 2SH
PHSC 6218 / Biomedical and Chemical Analysis / 2SH
NNMD 7270 / Introduction to Nanomedicine / 3SH
PHSC 6984 / Research / 2SH
PHSC 5976 / Directed Study / 1SH
PHSC 6300 / Seminar (Journal Club) 1SH

Total number of credits 45 SH

*Students coming in with a Master’s degree must complete the 12 SH for the PhD core courses and any other courses deemed necessary by the committee members.

Pharmaceutical Sciences (PhD): Interdisciplinary Concentration

The interdisciplinary specialization is intended to meet the needs of students interested in combining courses and skills from two areas of specialization. At least one of the specialization areas must come from within the college. The second area may come from a department in another college at Northeastern University, such as Biology, Chemistry, or Engineering. Dissertation coadvisers are arranged for students who elect this option.

Students may begin to consider this option by discussing it with a faculty member in the college representing one of their areas of interest and by informing the PhD program director’s office. The two areas of academic concentration are reflected in the course work, cumulative exams, and dissertation work undertaken. Students take the usual required courses. Specialization and General Elective Core courses are approved by the coadvisers. Students electing the interdisciplinary option must fulfill the same requirements as all other PhD candidates.

Doctoral students receive tuition waivers and usually receive stipends for research or teaching of $25,000-$30,000/year.

Curriculum

Pharmaceutical Science Core 5-6 SH
PHSC 5100 / Concepts in Pharmaceutical Science / 2 SH
PHSC 6210 / Drug Design, Evaluation and Development / 2 SH
PHSC 6212 / Research Skills and Ethics / 1 SH or
BIOL 6381 / Ethics in Biological Research / 2 SH

Interdisciplinary Specialization Core at least 24 SH
PHSC 7010 / PharmSci Lab / 4 SH
PHSC 6214 / Experimental Design and Biometrics / 2 SH
PHSC 6216 / Human Physiology and Pathophysiology / 2 SH
PHSC 6218 / Biomedical Chemical Analysis / 2 SH
Studenst must take either:
BIOL 6300 / Graduate Biochemistry / 4 SH OR
PHSC 5300 / Pharmaceutical Biochemistry / 2 SH AND
BIOL 6301 / Molecular Cell Biology / 4 SH OR
PHSC 5310 / Cellular Physiology / 2 SH

Any PMCL or PMST course
BIOL 5579 / Biochemistry Methods Laboratory / 5 SH
CHEM 5612 / Principles of Mass Spectrometry / 3 SH
CHEM 5626 / Organic Synthesis I / 3 SH
CHEM 5628 / Spectroscopy of Organic Compounds / 3 SH
CHEM 5676 / Bioorganic Chemistry / 3 SH

PhD Core 12 SH minimum
PHSC 6300 / Pharmaceutical Science Seminar / 1 SH (must be taken more than once)
PHSC 8940 / Doctoral Training & Research / 1 SH (Qualifying Exam Preparation)
PHSC 9681 / Doctoral Proposal / 2 SH
PHSC 6810 / Pharmaceutical Science Colloquium / 1 SH
PHSC 9990 / Dissertation / 3 SH (must be taken twice)

General Elective Core 4-6 SH
Advisor consultation is required when choosing electives

Total number of credits 45 SH

*Students coming in with a Master’s degree must complete the 12 SH for the PhD core courses and any other courses deemed necessary by the committee members.

Graduate Industrial Fellowship Program

A doctoral student in the Department of Pharmaceutical Sciences received an Industrial Fellowship and is currently working on a joint research project to understand the mechanism of vaccine adjuvants. The Academic-Industrial partnership established through the Fellowship has created unprecedented opportunities leveraging strengths from the two sectors. Doctoral students gain real-world perspective from industrial partnership, while still maintaining freedom to present and publish.

We invite you to consider supporting this innovative model of graduate-level scientific training. Important questions that are raised in industry can be answered in collaboration with us through a comprehensive doctoral thesis. Based on the diversity of faculty research interests in the Department, the projects can range from Drug Discovery/Medicinal Chemistry, Pharmacology, Toxicology, Drug Delivery, Nano-Biotechnology, Bioanalytical Chemistry, and Imaging.

Please contact us for additional information and a discussion on how partnering together we can advance the discovery and development of therapeutics and vaccines.

Non-Traditional PhD
Non-traditional PhD Policies as of 9/17/2013

  1. Prospective PhD student entering through the non-traditional pathway will first require a faculty sponsor/mentor.
  2. There will be no departmental financial aid available to PhD students who enter through the non-traditional pathway.
  3. Transcripts and other application material need to be submitted by the candidate and will be reviewed by the Graduate Committee. The Graduate Committee will serve as a primary screen for eligibility of the candidate into our doctoral program.
  4. A prior MS degree in Pharmaceutical Sciences or a related field (as determined by the Graduate Committee) is required. If the degree is awarded from Northeastern University, the candidate will be exempt from didactic courses. If the degree is awarded from another institution, the Graduate Committee will review the transcripts to evaluate any deficiencies and proper coursework for progress. All students will take the following:Ph.D. Courses – 12 SH minimum• PHSC 6300 Pharmaceutical Science Seminar 1 SH (must be taken more than once)
    • PHSC 8940 Doctoral Training and Research, 1 SH
    • PHSC 9681 Doctoral Proposal 2 SH
    • PHSC 6810 Pharmaceutical Science Colloquium 1 SH
    • PHSC 9990 Dissertation 3 SH (must be taken at least twice, no more than 3 times)
  5. If the candidate meets our admission requirements, he/she will be asked to visit the campus and meet with the faculty mentor. The supervisor/sponsor from the company will also join this meeting.
  6. At this meeting, the candidate and sponsor from industry will work with the faculty mentor to develop a student progression plan and preliminary dissertation research proposal. Tuition and research expenses will be included in the student progression plan.
  7. The progression plan and dissertation proposal will be formally presented to the University through the Technology Transfer Office. Any confidentiality/IP issues will be addressed through the Technology Transfer Office and the company lawyer(s). The dissertation work must be open to publication and presentation.
  8. Upon completion of the agreement between the University and the company, the progression plan and the dissertation proposal will be submitted to the Graduate Committee.
  9. The student will be formally accepted into the doctoral program.
  10. The candidate will be expected to meet the departmental requirements and pass the qualifying exam, defend the dissertation research proposal, attend departmental seminars, provide progress reports, and successfully defend the dissertation preferably within a period of 3 years but no more than 5 years after the qualifying exam.
  11. Every 6 months, the Graduate Committee will request that the faculty mentor provide a written status of the candidate’s progress towards PhD.

PhD Students

Abhijit Kulkarni, faculty advisor: Thakur

Aditi Jhaveri, faculty advisor: Torchilin

Amirah Aly, faculty advisor: Waszcazk

Anisha Korde, faculty advisor: Makriyannis

Bhawani Aryasomayajula, faculty advisor: Torchilin

Bhushan Pattni, faculty advisor: Torchilin

Bo Peng, faculty advisor: Makriyannis

Brijesh Garg, faculty advisor: Loring

Chandrashekar Honrao, faculty advisor: Makriyannis

Charles Perry, faculty advisor: Booth

Christina Miyabe, faculty advisor: Makriyannis

Daniel Ferreira Gomes Costa, faculty advisor: Torchilin

Girija Rajarshi, faculty advisor: Makriyannis

Helal Alsulimani, faculty advisor: Kim

Hiral Patel, faculty advisor: Loring

Husain Attarwala, faculty advisor: Amiji

Jimit GirishRaghav, faculty advisor: Makriyannis

JuOae Chang, faculty advisor: Kim

Khadijah Mohammad, faculty advisor: Makriyannis

Kun Qian, faculty advisor: Gatley

Livia Palmerston Mendes, faculty advisor: Torchilin

Michael Johnson, faculty advisor: Makriyannis

Mohammad Baradwan, faculty advisor: Makriyannis

Murillo Silva, faculty advisor: Sitkovsky

Murui Han, faculty advisor: Kim

Pooja Naresh Sabhachandani, faculty advisor: Konry

Pranali Prabhakar Deshpande, faculty advisor: Torchilin

Prashant Bhattari, faculty advisor: Khaw

Qi Ye, faculty advisor: Kim

Radhika Narayanaswamy, faculty advisor: Torchilin

Ruchi Shah, faculty advisor: Amiji

Sean Koncur, faculty advisor: Gatley

Shashank Kulkarni, faculty advisor: Makriyannis

Shilpa Sonti, faculty advisor: Gatley

Shravan Kumar Sriraman, faculty advisor: Torchilin

Srikrishnan Mallipeddi, faculty advisor: Makriyannis

Sunita Yadav, faculty advisor: Amiji

Terrence Hall, faculty advisor: Gatley

Thomas Barchet, faculty advisor: Ferris

Verbena Kosovrasti, faculty advisor: Amiji

Wen Zhang, faculty advisor: Makriyannis

Wenjun Di, faculty advisor: Clark

Xin Sun, faculty advisor: Makriyannis

Yi Luo, faculty advisor: Clark

Yingpeng Liu, faculty advisor: Makriyannis

Yiting Lee, faculty advisor: Deth

Yuanyuan Yao, faculty advisor: Giese

Apply to a PhD Program