Title:  Associate Professor
Director, Critical Care Pharmacy Fellowship Program

Department:  Department of Pharmacy Practice

School/Center:  School of Pharmacy

Office Location:  206 Mugar Hall

Phone:  617-373-8171

Fax:  617-373-7655

Email:  j.devlin@neu.edu

Education:  Post-doctoral research fellow, Henry Ford Hospital, Detroit, MI
Practice Residency, London Health Sciences Center
Doctor of Pharmacy, University of Toronto
Bachelors of Science in Pharmacy, University of Toronto

Certification:  Board Certified Pharmacotherapy Specialist (BCPS)

Specializations:  Critical Care

Research:  Clinical investigations surrounding the assessment and treatment of delirium and agitation in the intensive care unit and acute acid suppression.
Research site:  Tufts Medical Center. Email: j.devlin@tufts-nemc.org

Courses:  
Research Methods in Health Systems (PMD U585) This 5th year elective course will expose students to the research methods that health system pharmacists use most often when conducting research.
Critical Care Advance Practice Experience (PMD G441).  This 6th year practice experience allows students to focus on either conducting clinical research in the ICU or providing clinical pharmacy services in the ICU.

Selected Publications:  
1. Devlin, J.W,  Roberts, R., Fong, J.J., Skrobik, Y., Riker R.R., Hill, N.S., Garpestad, E. Efficacy and safety of quetiapine for delirium in the ICU: A randomized, double-blind, placebo-controlled pilot study.  Critical Care Medicine. Ahead of press Nov 4 2009

2. Roberts, R. Barletta, J., Fong, J., Schumaker, G., Gerlach, T., Voils, S., Kuper, P., Szumita, P., Anger, K., Papadopoulos, S., Grgurich, P., Kendall, E., Xamplas, R., Arpino, P., Ruthazer, R., Devlin, J.W. Incidence of the propofol infusion syndrome in critically ill adults. Critical Care. Crit Care. 2009 Oct 29;13(5):R169.

3. Tanios, M.A., Epstein S.K., de Wit, M., Devlin, J.W. (2009). Perceived barriers to the use of sedation protocols and daily sedation interruption. A multidisciplinary survey. Journal of Critical   Care 24;66-73.

4. Fong, J.J., Devlin, J.W., (2009) Can post-operative delirium be prevented pharmacologically?  Critical Care Medicine 37:1825-6.

5. Devlin, J.W., Roberts R. (2009) Pharmacology of commonly used sedatives and analgesics in the ICU. Critical Care Clinics 25: 431-49. 

6. Erstad, B.L., Brophy, G.M., Martin, S.M., Haas, C.E., Devlin, J.W., Welage, L.S., Dager, W. (in press) Articles and guidelines relative to intensive care init pharmacology: a 2009 update. Pharmacotherapy.

7. Devlin, J.W., Fong J., Howard, E., Skrobik, Y., McCoy N., Yasuda C., Marshall, J. (2008). Assessment of delirium in the intensive care unit: Nursing practices and perceptions. American Journal of Critical Care 17:555-65.

8. Fong, J., Sylvia, L., Ruthazer, R., Schumaker, G., KComt, M., Devlin, J.W., (2008). Predictors of mortality in patients with propofol infusion syndrome. Critical Care Medicine 36:2281-7.

9. Devlin, J.W. (2008) The pharmacology of oversedation in mechanically ventilated adults. Current Opinions in Critical Care 14:403-7.

10. Lancaster, J., Lawrence, K., Fong, J., Doron, S., Garpestad, E., Nasraway S, Devlin, J.W. (2008). Impact of an institutional hospital-acquired pneumonia protocol on the appropriateness of antibiotic therapy and patient outcomes. Pharmacotherapy. 28:852-62.

11. Olsen, K.M., Devlin, J.W. (2008). Comparison of oral and intravenous lansoprazole pharmacodynamic response in the critically ill. Alimentary Pharmacology and Therapeutics, 28:326-333.

12. De Wit, M., Devlin, J.W. (2008). Should sedation be standardized in the ICU? Critical Care Medicine, 36:1649-51.

13. Roberts, R., Welch, S., Devlin, J.W. (2008) Corticosteroids for the prevention of post-extubation laryngeal edema in adults. Annals of Pharmacotherapy, 42:686-91.

14. Barletta, J.F., Devlin, J.W. (2008). Sedation with dexmedetomidine vs lorazepam in mechanically ventilated patients. Journal of the American Medical Association, 299:1541.

15. Metz, D.C., Devlin, J.W., Vakily, M., Atkinson, S., Lloyd, S. (2008). Administering lansoprazole 30 mg as a 2-minute intravenous injection provides greater immediate gastric acid suppression than a 30-minute infusion. Pharmacotherapy,28:301-7.

16. Devlin, J.W., Marquis, F., Riker, R.R., Robbins, T., Garpestad, E., Fong, J.J., Didomenico, D. & Skrobik, Y.S. (2008). Combined didactic and scenario-based education improves the ability of ICU staff to recognize delirium at the bedside. Critical Care,12:R19.

17. Devlin, J.W., Nasraway, S.A. (2008). Reversing oversedation in the ICU: The role of pharmacists in energizing guideline efforts and overcoming protocol fatigue. Critical Care Medicine,36:626-8.

18. Devlin, J.W., Fong, J.J., Schumaker, G., Ruthazer, R., O’Connor, H. & Garpestad, E. (2007). Use of a validated delirium assessment tool improves the ability of physicians to recognize delirium in medical intensive care unit (MICU) patients. Critical Care Medicine, 35; 2721-4.

19. Van Amburgh, J., Devlin, J.W., Kirwin, J., Qualters, D. (2007) The active learning inventory: A tool to measure active learning in the classroom. American Journal of Pharmacy Education,71:85-93.

20. Fong, J.J., Kanji, S., Dasta, J., Garpestad, E., & Devlin, J.W. (2007). Propofol is associated with a shorter duration of mechanical ventilation than scheduled intermittent lorazepam: A database analysis using Project IMPACT. Annals of Pharmacotherapy, 41:1986-1991.

21. Devlin, J.W., Nava, S., Fong, J.J., & Hill, N.S. (2007). Survey of sedation practices during noninvasive positive-pressure ventilation to treat acute respiratory failure. Critical Care Medicine, 35:2298-2302.

22. Fong, J.J., Cecere, K., Klee, M., Garpestad, E., Unterborn, J., & Devlin, J.W. (2007).  Factors influencing variability in compliance rates and clinical outcomes among three different severe sepsis bundles. Annals of Pharmacotherapy, 41, 929-36.

23. Devlin, J.W., Fong, J., Fraser, G., & Riker, R. (2007) Delirium assessment in the critically Ill. Intensive Care Medicine, 33, 929-40.

24. Rea, R., Battistone, S., Fong, J., & Devlin, J.W. (2007). Atypical antipsychotics versus haloperidol for treatment of delirium in acutely ill patients. Pharmacotherapy, 27:588-594.
 
25. Devlin, J.W., Bakshi, A., Bungay, K.M., & Olsen, K.M. (2006) An in vitro comparison of different providers to deliver four proton pump inhibitor (PPI) products through a feeding tube. Alimentary Pharmacology and Therapeutics, 24,1603-1613.

26. Kane-Gill, S., & Devlin, J.W.  (2006). Adverse drug event reporting in the intensive care unit: A survey of current practices. Annals of Pharmacotherapy, 40,1267-1273.
 
27. MacLaren, R., Devlin, J.W., Martin, S.J., Dasta, J.F., Rudis, M.I., & Bond, C.A. (2006). A national survey characterizing the practice of critical care pharmacists. Annals of Pharmacotherapy, 40, 612-618.

28. Devlin, J.W., Tanios, M., & Epstein, S.K. (2006). ICU sedation: Waking up clinicians to the gap between research and practice. Critical Care Medicine, 34, 556-557.

29. Devlin, J.W., & Olsen, K.M. (2006).Proton pump inhibitor formulary considerations in the acutely ill: Part 1: Pharmacology, pharmacodynamics and available formulations. (Author’s reply). Annals of Pharmacotherapy, 40, 997-998.

30. Devlin, J.W., Fong, J.J., & Schumaker, G. (2006) Identifying factors that could account for differences in duration of mechanical ventilation between intermittent lorazepam and propofol-treated patients. Critical Care Medicine, 34, 3063-3064.

31. Devlin, J.W., Lau, A.K., & Tanios, M. (2005). Propofol-associated hypertriglyceridemia and pancreatitis in the ICU: An incidence and risk factor analysis. Pharmacotherapy, 25,1348-1352.

32. Ahrens, C.L., Barletta, J.F., Kanji, S., Tyburski, J.G., Wilson, R.F., Janisse, J.J., & Devlin, J.W. (2005). The effect of low-calorie parenteral nutrition on the incidence and severity of hyperglycemia in surgical patients: A randomized, controlled trial. Critical Care Medicine, 33, 2507-2512.

33. Devlin, J.W., & Barletta, J.F. (2005). Reevaluating the role of albumin for fluid resuscitation: Implications of the saline versus albumin fluid evaluation (SAFE). American Journal of Health-System Pharmacy, 62, 637-642.

34. Devlin, J.W., Welage, L.S., & Olsen, K.M.  (2005).Proton pump inhibitor formulary considerations in the acutely ill: Part 1: Pharmacology, pharmacodynamics and available formulations. Annals of Pharmacotherapy 2005, 39, 1667-1677.

35. Devlin, J.W., Welage, L.S., & Olsen, K.M. (2005) Proton pump inhibitor formulary considerations in the acutely ill: Part 2: Clinical efficacy, safety and economics. Annals of Pharmacotherapy, 39, 1844-1851.

36. Devlin, J.W. (2005).Treatment options and formulary considerations in the management of acid suppression in critically ill patients. American Journal of Health-System Pharmacy, 62(Suppl 2), S2-3.

37. Devlin, J.W. (2005). Proton pump inhibitors for acid suppression in the intensive care unit: Formulary considerations. American Journal Health-System Pharmacy 62, (Suppl 2), S24-30.

38. Devlin, J.W., Seta M.L., Kanji, S., & Somerville, A.L. (2004). Fenoldopam versus nitroprusside for the treatment of hypertensive emergency. Annals of Pharmacotherapy, 38, 755-759.

39. Diebel, L.N., Liberati, D.M., Baylor, A.E., Brown, W.J., & Devlin, J.W. (2004). Immunogloobulin A protease is a virulence factor for gram-negative pneumonia. Surgery, 136, 937-943.

40. Nguyen, C.M., Barletta, J.F., & Devlin J.W. (2004). Use of acid suppression agents following acute, non-variceal, upper gastrointestinal bleeding. Hospital Pharmacy, 39, 970-975.

41. Devlin, J.W., & Welage, L.S. (2004). The cost effectiveness of proton pump inhibitors for bleeding peptic ulcers: The unanswered questions. Critical Care Medicine, 32, 1415-1416.

42. Betancourt, M., McKinnon, P.S., Massanari, R.M., Kanji, S., Bach, D., & Devlin, J.W. (2003). An evaluation of the cost effectiveness of drotrecogin alfa (activated) relative to the number of organ system failures. PharmacoEconomics, 21(18), 1331-1340.

43. Kanji, S., McKinnon, P.S., Barletta, J.F., Kruse, J.A., & Devlin, J.W.(2003). Bioavailability of gatifloxacin by nasogastric administration with and without concomitant enteral feeding in critically ill patients. Critical Care Medicine, 31, 1347-1352.

44. Maccioli, G.A., Dorman, T., Brown, B.R., Mazuski, J.E., McLean, B.A., Kuszaj, J.M., Rosenbaum, S.H., Frankel, L.R., & Devlin, J.W. (2003). Clinical practice guidelines for the maintenance of patient physical safety in the intensive care unit: Use of restraining therapies – American College of Critical Care Medicine Task Force 2001-2002. Critical Care Medicine, 31, 2665-2676.

45. Kanji, S., Barletta, J.F., Janisse, J., Kruse, J.A., & Devlin, J.W. (2002). Tachyphylaxis associated with continuous cisatracurium versus pancuronium therapy. Pharmacotherapy, 22, 823-830.

46. Delgado, G., Barletta J.F., Kanji, S., Tyburski, J.G., Wilson, R.F., & Devlin, J.W. (2002). Characteristics of prophylactic antibiotic strategies following penetrating abdominal trauma at a level one urban trauma center: A comparison to the EAST Guidelines. Journal Trauma, 53, 673-678.

47. Vanscoy, G., Devlin, J.W., Ponzillo, J., & Kuhl, D.A. (2002). Implementing guidelines for drotrecogin alfa (activated): Three perspectives. Pharmacy and Therapeutics, 27, 1-15.

48. Devlin, J.W., & Kanji, S. (2002). Managing thrombosis syndromes. In: Critical Care Module, Pharmacy Self Assesssment Program (PSAP). 4th ed.  Zarowitz, BJ. (Ed). Kansas City, MO, American College of Clinical Pharmacy.

49. Devlin, J.W., Tyburski, J.G., & Moed, B. (2001). Implementation and evaluation of enoxaparin deep vein thrombosis prophylaxis guidelines after major trauma. Pharmacotherapy, 21,740-747.

50. McKinnon, P.S., Goff, D.A., Kern, J.W., Devlin, J.W., Barletta, J.F., Sierawski, S.J., Mosenthal, A.C., Gore, P., Ambegaonkar, A.J., & Lubowski, T.J. (2001) Temporal assessment of candida risk factors in the surgical intensive care unit. Archives of Surgery, 136, 1401-1409.

51. Tyburski, J.G., Dente, C., Wilson, R.F., Steffes, C., Devlin, J.W., Carlin, A., & Shanti, C. (2001). Differences in arterial and mixed venous IL-6 levels: The lungs as a source of cytokine storm in sepsis. Surgery, 130, 748-752.

52. Devlin, J.W., Fraser, G.F., Kanji, S., & Riker, R. (2001). Sedation assessment in critically ill adults.  Annals of Pharmacotherapy, 35, 1624-1632.

53. Kanji, S., Devlin, J.W., Piekos, K., & Racine, E. (2001). Recombinant human activated protein C (drotrecogin alfa activated): A novel therapy for severe sepsis. Pharmacotherapy, 21, 1389-1402.

54. Devlin, J.W., Coplin, W.M., Murry, K.R., Rengachary, S.S., & Wilson, R.F. (2000). Nimodipine induced acute hypoxemia. Neurosurgery, 47, 1243-1247.

55. Devlin, J.W. Pain assessment in seriously ill patients: Can family members play a role? Critical Care Medicine, 28, 1660-1661.

56. Clemmer, T.P., Wallace, J.C., Spuhler, V.J., Bailey, P.P., & Devlin, J.W. (2000). Origins of the Motor Activity Assessment Scale score: A multi-institutional process. Critical Care Medicine 28, 3124.

57. Devlin, J.W. (2000). The role of low molecular weight heparin for DVT prophylaxis in acutely ill medical patients.  Journal of Informed Pharmacotherapy 2000; 3, 300-308.

58. Devlin, J.W., Boleski, G., Mlynarek, M., Nerenz, D., Peterson, E., Horst, H.M., & Zarowitz, B.J. (1999). The Motor Activity Assessment Scale: A valid and reliable sedation scale for use in adult, mechanically ventilated, surgical ICU patients. Critical Care Medicine, 27, 1271-1275.

59. Mazur, J.E., Devlin, J.W., Peters, M.J., Jankowski, M., Iannuzzi, M.C., & Zarowitz, B.J. (1999) Single versus multiple doses of acetazolamide for metabolic alkalosis in critically ill medical patients: A randomized, double-blind trial. Critical Care Medicine, 27, 1257-1261.

60. Devlin, J.W., Claire, K.S., Dulchavsky, S.A., &Tyburski, J.G. (1999). Impact of trauma stress ulcer prophylaxis guidelines on drug cost and incidence of major gastrointestinal bleeding. Pharmacotherapy, 19, 452-460.

61. Devlin, J.W., Pettita, A., Shepard, A., & Obeid, F.N. (1998). Cost-effectiveness of enoxaparin versus low-dose heparin as prophylaxis against venous thrombosis after major trauma. Pharmacotherapy,18, 1335-1342.

62. Devlin, J.W., Peters, M., Ulep, S., Ben-Menachem, T., Fogel, R., & Zarowitz, B.J. (1998). Stress ulcer prophylaxis in medical ICU patients: Annual utilization in relation to the incidence of endoscopically-proven stress-related gastritis. Annals of Pharmacotherapy, 32, 869-874.

63. Makarechian, N., Agro, K.A., Devlin, J.W., Trepanier, E.R., Einarson, T., & Koren, G. (1998). Association between moderate alcohol consumption during pregnancy and spontaneous abortion, stillbirth, and premature birth: A meta-analysis. Canadian Journal of Clinical Pharmacology, 5(3),169-176.

64. Devlin, J.W., Holbrook, A.M., & Fuller, H.D. (1997). The effect of ICU sedation guidelines and pharmacist interventions on clinical outcomes and drug cost. Annals of Pharmacotherapy, 31, 689-695.

65. Devlin, J.W., Bailey, E.M., & Zarowitz, B.J. (1997). Administration of amphotericin B in lipid emulsion. Critical Care Medicine, 25, 892.