Title: Professor
Department: Department of Pharmaceutical Sciences
School/Center: School of Pharmacy
Office Location: 110 Mugar Hall
Phone: 617.373.3137
Fax: 617.373.8886
Email: m.amiji@neu.edu
Education: BS, Pharmacy (magna cum laude), Northeastern University
PhD, Pharmaceutics, Purdue University
Certification: Registered Pharmacist in MA
Specializations: Polymeric Biomaterials
Drug Delivery Systems
Nanomedical Technologies
Research: Synthesis of novel polymeric materials for medical and pharmaceutical applications.
Surface modification of cationic polymers by the complexation-interpenetration method to develop biocompatible materials.
Preparation and characterization of polymeric membranes and microcapsules with controlled permeability properties for medical and pharmaceutical applications.
Target-specific drug and vaccine delivery systems for gastro-intestinal tract infections.
Localized delivery of cytotoxic and antiangiogenic drugs for solid tumors in novel biodegradable polymeric nanoparticles.
Intracellular delivery systems for drugs and genes using target-specific, long-circulating, biodegradable polymeric nanoparticles.
Gold and iron-gold core-shell nanoparticles for biosensing, imaging, and delivery applications.
Publications: Books
Amiji, M.M. and Sandmann, B.J. Applied Physical Pharmacy. McGraw-Hill Medical Publishing Division. New York, NY. 2002.
Amiji, M.M. Polymeric Gene Delivery: Principles and Applications. CRC Press, LLC. Boca Raton, FL. (In press).
Manuscripts
Amiji, M.M., Lai, P.-K., Shenoy, D.B., and Rao, M. Intratumoral administration of paclitaxel in an in situ gelling poloxamer 407 formulation. Pharmaceutical Development and Technology. 7(2): 195-202 (2002).
Hejazi, R. and Amiji, M. Stomach-specific anti-H. pylori therapy. I: Preparation and characterization of tetracycline-loaded chitosan microspheres. International Journal of Pharmaceutics 235(1-2): 87-94 (2002).
Nsereko, S. and Amiji, M. Localized delivery of paclitaxel in solid tumors from biodegradable chitin microparticle formulations. Biomaterials 23(13): 2723-2731 (2002).
Kaul, G. and Amiji, M. Long-circulating poly(ethylene glycol)-modified gelatin nanoparticles for intracellular delivery. Pharmaceutical Research 19 (7): 1062-1068 (2002).
Kaul, G., Potineni, A., Lynn, D.M., Langer, R., and Amiji, M.M. Surface-modified polymeric nanoparticles for tumor-targeted delivery. surFACTS – Official Newsletter of Surfaces in Biomaterials Foundation. 7(2): 1-6 (2002).
Chawla, J.S. and Amiji, M.M. Biodegradable poly(?-caprolactone) nanoparticles for tumor-targeted delivery of tamoxifen. International Journal of Pharmaceutics 249 (1-2): 127-138 (2002).
Taqieddin, E., Lee, C., and Amiji, M. Perm-selective chitosan-alginate hybrid microcapsules for enzyme immobilization technology. Pharmaceutical Engineers – Journal of the International Society of Pharmaceutical Engineers. 22 (6): 112-114 (2002).
Potineni, A., Lynn, D.M., Langer, R., and Amiji, M.M. Poly(ethylene oxide)-modified poly(?-amino ester) nanoparticles as pH-sensitive biodegradable system for paclitaxel delivery. Journal of Controlled Release. 86: 223-234 (2003).
Chawla, J.S. and Amiji, M.M. Cellular uptake and concentrations of tamoxifen upon administration in poly(?-caprolactone) nanoparticles. AAPS PharmSci 5 (1): Article 3 (2003). (http://www.pharmsci.org).
Hejazi, R. and Amiji, M. Chitosan-based gastrointestinal delivery systems. Journal of Controlled Release. 89: 151-165 (2003).
Hejazi, R. and Amiji, M. Stomach-specific anti-H. pylori therapy. II: Gastric residence studies of tetracycline-loaded chitosan microspheres in gerbils. Pharmaceutical Development and Technology. 8: 253-262 (2003).
Kaul, G., Lee-Parsons, C., and Amiji, M. Poly(ethylene glycol)-modified gelatin nanoparticles for intracellular delivery. Pharmaceutical Engineers – Journal of the International Society of Pharmaceutical Engineers. 23 (5): 108-114 (2003).
