Mark A. Tracy

President
Tracy BioConsulting, LLC

Adjunct Associate Professor, Department of Pharmaceutical Sciences
Academic Advisor, Biotechnology PSM Program

Northeastern University

Phone: 617.417.7163
Email: m.tracy@neu.edu

Degrees/Education

Ph.D., Chemistry, Stanford University
M.S., Chemical Engineering, Stanford University
B.S., Chemical Engineering, University of Illinois

Area(s) of Expertise

Pharmaceutical development and drug delivery

Research Interests

Protein, peptide, nucleic acid, and small molecule drug delivery and product development
Nanotechnology

Intracellular Delivery

Selected Publications

“Maximizing the Potency of siRNA Lipid Nanoparticles for Hepatic Gene Silencing In Vivo,” M. Jayaraman et al., Ang. Chemie, 51 (2012), 8529-33.

“Preface,” D.J. Burgess and M.A. Tracy, Drug Del. and Transl. Res., 1 (2011), 2-3.

“Developing siRNA Therapies:  A Technical Forum,” A. Pellek, M.A. Tracy, M. Houston, and J. Thompson, Pharmaceutical Technology, 34 (2010), 39-41.

“Targeted Delivery of RNAi Therapeutics with Endogenous and Exogenous Ligand-Based Mechanisms,” A. Akinc et al., Mol. Ther., 18 (2010), 1357-64.

“Rational Design of Cationic Lipids for siRNA Delivery”, S.C. Semple et al., Nature Biotech., 28 (2010), 172-6.

“Protein Spray Freeze Drying. 2. Effect of Formulation Variables on Particle Size and Stability” H.R. Costantino, L. Firouzabadian, C. Wu, K.G. Carrasquillo, K. Griebenow, S.E. Zale, and M.A. Tracy, J.Pharm. Sci., 91 (2002), 388-395.

Biomaterials for Drug Delivery and Tissue Engineering, ed. by S. Mallapragada, M. Tracy, B. Narasimhan, E. Mathiowitz, and R. Korsmeyer, MRS Symposium Proceedings Series, vol. 662, 2001.

“Protein Spray-Freeze Drying.  Effect of Atomization Conditions on Particle Size and Stability,” H.R. Costantino, L. Firouzabadian, K. Hogeland, C. Wu, C. Beganski, K.G. Carrasquillo, M. Cordova, K. Griebenow, S.E. Zale, and M.A. Tracy, Pharm. Res., 17 (2000), 1374-83.

“Peptide and Protein Drug Delivery,” O.L. Johnson and M.A. Tracy in Encyclopedia of Controlled Drug Delivery, ed. by E. Mathiowitz, John Wiley and Sons, 1999, 816-833.

“Characterization of Delivery Systems, Particle Sizing Techniques,” K.L. Ward and M.A. Tracy in Encyclopedia of Controlled Drug Delivery, ed. by E. Mathiowitz, John Wiley and Sons, 1999, 250-255.

“Factors Affecting the Degradation Rate of Poly(lactide-co-glycolide) Microspheres In vivo and In vitro,” M.A. Tracy, K.L. Ward, L. Firouzabadian, Y. Wang, N. Dong, R. Qian, and Y. Zhang, Biomaterials, 20 (1999), 1057-1062.

“Sustained Delivery of Proteins for Novel Therapeutic Products,” R.T. Bartus, M.A. Tracy, D.F. Emerich, S.E. Zale, Science, 281 (1998), 1161-1162.

“Development and Scale-up of a Microsphere Protein Delivery System,” M.A. Tracy, Biotechnology Progress, 14 (1998), 108-115.           

“A Large-Scale Process to Produce Microencapsulated Proteins,” P. Herbert, K. Murphy, O.L. Johnson, W. Jaworowicz, M.A. Tracy, J.L. Cleland, and S.D. Putney, Pharm. Res.,15 (1998), 357-58.