The Biotechnology Initiative
Research Interests

Learn more about research at Northeastern.

Ronald Aaron
Impedance measurements of muscle and clinical applications

Mansoor Amiji
Polymeric biomaterials and drug delivery systems

Joseph Ayers
Underwater robots modeled on lobster/lamprey nervous system

Penny Beuning
DNA damage tolerance using protein engineering, biophysical and biochemical techniques, and genetics

Norman Boisse
Neuropharmacology of benzodiazepines

Matthew Bracken
Organisms' roles in mediating the transformation and flux of energy and matter

David Budil
Application of high-frequency electron paramegnetic resonacne to studies of structure and dynamics in proteins; study of electron transfer and photophysics in biological systems

Rebecca Carrier
Drug delivery systems and modeling and tissue engineering

Paul Champion
Spectroscopic and femtosecond laser studies of heme proteins (e.g. cytochrome P450)

Donald Cheney
Macroalgal biotechnology and marine pollution remediation

Frederick Davis
Identifying the pacemaker(s) for the circadian clock

Richard Deth
Role of dopamine D4 receptors in schizophrenia and attention

William Detrich
Developmental disorders of red blood cell formation

Max Diem
Medical diagnoses of human cells and tissue sections by methods of spectral microscopy

John Engen
Protein conformation and dynamics by mass spectrometry

Craig Ferris
Molecular imaging (PET and SPECT) and MR imaging in drug discovery for the treatment of psychiatric and neurological disorders

David Forsyth
Applications of NMR; molecular orbital and molecular mechanics studies of structure; stereodynamics by NMR

S. John Gatley
Radionuclide imaging and pharmacology

Roger Giese
Bioanalytical detection of carcinogens and DNA adducts

April Gu
Application of biological processes and biotechnologies for removing nutrients and contaminants from water and wastewater

William Hancock
Cancer proteomics

Robert Hanson
Molecular modeling, conformational analysis (NMR) Stille and Suzuki coupling reactions multicomponent coupling reactions in combinatorial chemistry. Estrogen receptor subtype selective agents.

Graham Jones
Design and synthesis of antitumor agents; bioorganic chemistry enantioselective catalyst design; total synthesis of natural products

Barry Karger
Capillary electrophoresis; DNA sequencing; CE/MS; microchip/MS; microfluidics; multiplex on-line MALDI/TOF MS; proteomics; high throughput analysis; drug screening; protein and nucleic acid separation

Alain Karma
Using theoretical tools of nonlinear dynamics and computer simulations to understand the mechanisms of life-threatening irregular heart beats and identifying pharmagological targets for preventing ventricular fibrillation, the leading cause of US deaths

Ban-An Khaw
Cardiovascular disorders, immunology, and drug targeting

Carolyn Lee-Parsons
Secondary metabolite production from plant cell cultures and metabolic engineering

Kim Lewis
Culturing previously unculturable microorganisms

Ralph Loring
Neuronal nicotinic receptor assembly and composition

Patricia Mabrouk
Electrochemistry; Raman spectroscopy; direct electrochemistry of metalloproteins in unconventional media; structure-function studies of enzymes in non-aqueous media; conducting polymers

Alexandros Makriyannis
The endocannabinoid system in drug discovery

James Manning
Blood substitutes modeled on hemoglobin

Richard Marsh
Control of the energy cost for locomotion

George O'Doherty
Carbohydrate synthesis and natural product synthesis

Donald O'Malley
Neuronal imaging; global mapping of neural activity

Shashi Murthy
Microfluidic cell separation and biomaterial coatings for neuroprosthetics

Mark Niedre
In vivo imaging and tracking of fluorescently-labeled cells

Mary Jo Ondrechen
Theory: protein modeling; functional genomics; proteomics; computational studies of biomolecules

Jacqueline Piret
Antibiotic formation in streptomyces

Michael Pollastri
Discovery of new therapeutics for neglected tropical diseases

Susan Powers-Lee
Targeted design of proteins for ammonia detoxification

Rebeca Rosengaus
Disease susceptibility in complex insect societies

Robert Schatz
Environmental toxicology and regulation of metabolism

Michail Sitkovsky
Biochemistry and  immunopharmacology

Wendy Smith
Insulin Control of insect growth and development

Armen Stepanyants
Understanding principles governing synaptic connectivity, computational neuroanatomy

Dagmar Sternad
Research on learning and control of sensorimotor function and dysfunction in humans

Phyllis Strauss
Targeted control of DNA repair enzymes

Vladimir Torchilin
Targeted delivery of drugs and imaging agents

Steven Vollmer
Molecular evolution and ecology, marine genomics, and the genetics of disease resistance

Paul Vouros
Structural elucidation of organic compounds by mass spectrometry; trace analysis of organic compounds by GC-MS, applications to drug metabolism and environmental problems

Kai-tak Wan
Mechanical characterization and adhesion measurement of natural, malignant, and prosthetic cells and tissues

Philip Warner
Application of theoretical methods to problems in organic chemistry and biology

Barbara Waszczak
Neuropharmacology of the basal ganglia and its disorders

Mark Williams
Single molecule measurements of DNA-ligand interactions using optical tweezers

Zhaohui Sunny Zhou
Proteomics, protein chemistry and drug discovery

Gunther Zupanc
Behavioral, developmental, and comparative neurobiology; regenerative biology