Professor Barry L. Karger’s Research Group

  • Comprehensive characterization of large proteins using high resolution LC/MS
  • Trace proteomic analysis using ultra-narrow bore LC/MS
  • Clinical biomarker discovery for cancer

Professor William S. Hancock’s Research Group

  • Multiple Lectin Affinity Chromatography and the study of the glycoproteome
  • Glycan markers for the early detection of cancer
  • Application of proteomics to the study of protein pharmaceuticals

Professor John R. Engen’s Research Group

We use hydrogen exchange and mass spectrometry (HX MS) as our core technology to probe protein conformation, conformational changes, dynamics, protein folding and the effects of binding

Professor Graham B. Jones’ Research Group

Professor Jones’ research group is dedicated to the application of synthetic organic chemistry to the development of diagnostic and therapeutic agents. Since the mid-90’s the program has produced over 120 original research publications and attracted over $8 million in research funding. In most cases projects represent joint efforts between our NU program (housed in the Bioorganic & Medicinal Chemistry Laboratory) and collaborators at the nearby Harvard Medical School.

Professor Paul Vouros’ Research Group

  • Capillary LC-MS methods development for DNA adducts and drug metabolites
  • Ion Mobility Scanning (IMS-MS)

Professor Sunny Zhou’s Research Page

Professor Zhou’s group applies analytical, organic and protein chemistry, as well as biochemistry, enzymology and protein engineering to biology and medicine. Students actively collaborate with biologists and chemists alike in academia and industry all over the world.

Professor Roger W. Giese’s Research Group

  • Charge and electrophore tagging for ultrasensitive mass spectrometry
  • Characterization of genotoxic mixtures by mass spectrometry
  • Electrodialytic gel devices

Professor Jeffrey Agar’s Research Group

Mass Spectrometry and Neurodegenerative disease research including Parkinson’s disease and amyotrophic lateral sclerosis (ALS)

Professor Shashi K. Murthy’s Research Group

The primary focus of our research is the design of microfluidic devices for applications in clinical diagnostics and regenerative medicine. These devices are fabricated using technology originally designed for the semiconductor industry and are capable of handling and manipulating small volumes of fluids (down to tens of microliters) and small numbers of cells.