Research Groups

karger

Professor Barry L. Karger's Research Group
-  Comprehensive characterization of large proteins using high resolution LC/MS 
-  Trace proteomic analysis using ultra-narrow bore LC/MS 
-  Clinical biomarker discovery for cancer

Hancock

Professor William S. Hancock's Research Group
-  Multiple Lectin Affinity Chromatography and the study of the glycoproteome
-  Glycan markers for the early detection of cancer
-  Application of proteomics to the study of protein pharmaceuticals

Engen

Professor John R. Engen's Research Group

Current research projects in his laboratory include (1) investigations of kinase conformation to understand regulation and aberrant signaling in various disease states including cancer, (2) analysis of the conformation of viral accessory proteins from HIV, (3) studies of protein conformation at biological membranes, and (4) optimization and methods development in hydrogen exchange mass spectrometry.

Jones

Professor Graham B. Jones' Research Group

Professor Jones’ research group is dedicated to the application of synthetic organic chemistry to the development of diagnostic and therapeutic agents. Since the mid-90’s the program has produced over 120 original research publications and attracted over $8 million in research funding. In most cases projects represent joint efforts between our NU program (housed in the Bioorganic & Medicinal Chemistry Laboratory) and collaborators at the nearby Harvard Medical School. 

Vouros

Professor Paul Vouros' Research Group
-  Capillary LC-MS methods development for  DNA adducts and drug metabolites 
-  Ion Mobility Scanning (IMS-MS) 

Zhou

Professor Sunny Zhou's Research Page
Professor Zhou’s group applies analytical, organic and protein chemistry, as well as biochemistry, enzymology and protein engineering to biology and medicine. Students actively collaborate with biologists and chemists alike in academia and industry all over the world.

Giese

Professor Roger W. Giese's Research Group

-  Charge and electrophore tagging for ultrasensitive mass spectrometry
-  Characterization of genotoxic mixtures by mass spectrometry
-  Electrodialytic gel devices